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Radix pseudostellariae extracts and application thereof

The technology of extract and Radix Radix is ​​applied to the ethanol extract of Radix Radix Radix et Rhizoma in the preparation of medicines for treating diseases related to pulmonary qi deficiency, so as to achieve the effects of enhancing resistance, eliminating and relieving fatigue, and improving lung function.

Inactive Publication Date: 2013-04-03
FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no drug that can effectively control the development of COPD, and many countries regard it as a key prevention and treatment project for chronic diseases

Method used

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  • Radix pseudostellariae extracts and application thereof
  • Radix pseudostellariae extracts and application thereof
  • Radix pseudostellariae extracts and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1: 100 grams of dried medicinal materials of Pseudostellariae Pseudostellaria, soaked in 8 times the amount of 70% ethanol, placed in a pressurized continuous reflux extraction tank, the temperature of the oil in the extraction tank was 90°C, the temperature of the extract was 70°C, the pressure in the tank was 0.03 MPa, and the reflux extraction was performed for 3 Once, each time for 2 hours; combine the extracts, put them in a concentration tank, concentrate the oil at 85°C, concentrate at 30°C, and pressure -0.02 MPa, and concentrate to 1 / 20 of the original volume to obtain the ethanol extract extract.

Embodiment 2

[0018] Example 2: Take 200 grams of dried medicinal materials of Radix Pseudostellariae, add 10 times the amount of 95% ethanol to soak, and place it in a pressurized continuous reflux extraction tank. The temperature of the oil in the extraction tank is 130°C, the temperature of the extract is 90°C, and the pressure inside the tank is 0.06Mpa . Reflux extraction 3 times, 2 hours each time; combine the extracts, and then put the extracts in the concentration tank, the temperature of the concentrated oil in the concentration tank is 95°C, the temperature of the concentrate is 70°C, and the pressure is -0.05 Mpa. Concentrate to 1 / 25 of the volume of the extract to obtain the ethanol extract extract.

Embodiment 3

[0019] Example 3: 300 grams of dried medicinal materials of Radix Pseudostellariae, soaked in 9 times the amount of 80% ethanol, placed in a pressurized continuous reflux extraction tank, the temperature of the oil in the extraction tank is 110°C, the temperature of the extract is 80°C, and the pressure in the tank is 0.04MPa for reflux extraction for 3 times , 2 hours each time; combine the extracts, put them in a concentration tank, concentrate the oil at a temperature of 90°C, the temperature of the concentrate at 50°C, and a pressure of -0.04 MPa, and concentrate to 1 / 23 of the original volume to obtain an ethanol extract extract.

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Abstract

The invention provides three kinds of radix pseudostellariae extracts and applications thereof to preparation of drugs for treating lung-qi deficiency symptom related diseases. The three kinds of radix pseudostellariae extracts can suppress lung inflammation reactions, benefit qi and promote the production of body fluid, enhance resistance, recover immunologic balance, improve lung functions and eliminate and relieve such lung-qi deficiency symptoms as lack of strength, palpitation and shortness of breath. An improvement of lung-qi deficiency has great significance to control of frequently occurring and intractable lung diseases with the characteristic of recurrent attack.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a preparation method and application of an extract of Radix Pseudostellariae, in particular to a preparation method of ethanol extract and ethyl acetate extract of Radix Pseudostellariae, and three kinds of ethanol extract, ethyl acetate extract and polysaccharide The extract is used in the preparation of medicines for treating diseases related to lung qi deficiency. Background technique [0002] Deficiency of lung qi, from "Su Wen·Fang Sheng Hua Lun Pian", also known as lack of lung qi. It is mostly caused by cold and temperature discomfort, chronic cough and hurting Qi, endless sadness, and improper work and rest. Symptoms include coughing and shortness of breath, or even shortness of breath or dyspnea, excessive phlegm and clear thinness, fatigue, spontaneous sweating, weak or weak pulse. Deficiency of lung qi is the basic pathogenesis of lung system diseases, whic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/36A61P1/14A61P11/00
Inventor 胡娟庞文生林泗定戴启文张鸿程
Owner FUJIAN UNIV OF TRADITIONAL CHINESE MEDICINE
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