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Skin-whitening composition for external application on skin containing extracts from paper mulberry flowers and fruits

A composition for external use, a technology for skin whitening, which can be used in medical preparations containing active ingredients, preparations for skin care, skin diseases, etc., and can solve problems such as insufficient skin whitening effect, skin safety problems, and formula instability.

Inactive Publication Date: 2013-03-13
AMOREPACIFIC CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when they are applied to cosmetics, etc., their application is limited due to insufficient skin whitening effect, safety problem to skin, instability of formulation

Method used

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  • Skin-whitening composition for external application on skin containing extracts from paper mulberry flowers and fruits

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0017] Preparation Example 1: Preparation of Extracts of Flowers and Fruits of Paperwood

[0018] 1 kg of flowers and fruits of mulberry tree were added to 10 L of clean water, and extracted by boiling in an extractor equipped with a condenser for 5 hours. The extract was filtered through a 300-mesh filter cloth, kept at 5-15° C. for 5 days, and then filtered with filter paper. The filtrate was concentrated under reduced pressure in a distillation apparatus system equipped with a condenser, thereby obtaining 70 g of extracts of flowers and fruits of mulberry tree.

preparation example 2

[0019] Preparation Example 2: Preparation of Extracts from Leaves, Stems and Roots

[0020] 1 kg of leaves, stems and roots of mulberry tree were added to 10 L of clean water, and extracted by boiling in an extractor equipped with a condenser for 5 hours. The extract was filtered through a 300-mesh filter cloth, kept at 5-15° C. for 5 days, and then filtered with filter paper. The filtrate was concentrated under reduced pressure in a distillation apparatus system equipped with a condenser, thereby obtaining 70 g of extracts of leaves, stems and roots of mulberry trees.

Embodiment and comparative example 1 and comparative example 2

[0032] The lotion formulations (unit: wt %) of Example and Comparative Example 1 and Comparative Example 2 were prepared using the components shown in Table 2 below.

[0033] Table 2

[0034] Element Example Comparative example 1 Comparative example 2 1. Cetearyl alcohol 1.0 1.0 1.0 2. Lipophilic Glyceryl Stearate 1.0 1.0 1.0 3. Glyceryl Stearate SE 1.5 1.5 1.5 4. Phytosqualane 3 3 3 5. Hydrogenated polydecene 2 2 2 6. Dimethicone 0.5 0.5 0.5 7. Polysorbate 60 1 1 1 8. Sorbitan Sesquioleate 0.4 0.4 0.4 9. Methylparaben 0.1 0.1 0.1 10. Propylparaben 0.05 0.05 0.05 11. Pure water to 100 to 100 to 100 12. Butanediol 5 5 5 13. Polyacrylate-13*polyisobutylene*polysorbate 20 0.5 0.5 0.5 14. Extract of flowers and fruits of mulberry tree (preparation example 1) 1 - - 15. Extract of leaves, stems and roots of mulberry tree (preparation example 2) - 1...

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Abstract

The present invention relates to a composition for external application on skin, the composition containing extracts from flowers and fruits of paper mulberry, more specifically containing extracts from flowers and fruits of paper mulberry as an active ingredient, thereby enabling excellent skin-whitening effects through effective suppression of melanin formation.

Description

technical field [0001] The present invention relates to a composition for external use on skin containing extracts of flowers and fruits of paper mulberry, and more particularly, to a composition for external use on skin containing extracts of flowers and fruits of paper mulberry as an active ingredient A composition for external use on the skin exhibits an excellent skin whitening effect by effectively inhibiting the production of melanin. Background technique [0002] The color of human skin is determined by various factors, including the activity of melanocytes (melanocytes) that produce melanin pigment, the distribution of blood vessels, the thickness of the skin, the presence of pigments (such as carotenoids and bilirubin) or Does not exist etc. Among these factors, melanin (dark pigmentmelanin) produced by melanocytes through the action of various enzymes containing tyrosinase is the most important. Genetic factors, biological factors (such as hormone secretion, stre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61K8/97A61P17/00A61Q19/02
CPCA61K8/97A61K2800/782A61Q19/02A61K8/9789A61K36/60A61P17/00A61K2236/17A61K2236/331
Inventor 李真锳林亨峻
Owner AMOREPACIFIC CORP
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