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Lead removing traditional Chinese medicine composition

A technology of composition and traditional Chinese medicine, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of insignificant reversal of nerve damage, loss of trace elements, large side effects, etc. Effects with few side effects

Active Publication Date: 2013-12-18
LIAONING UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drugs for the clinical treatment of lead poisoning mainly include disodium calcium edetate (CaNa2EDTA), sodium dimercaptosuccinate (DMSA), etc. Although these drugs can reduce the lead load in the body and have a good lead-expelling effect, they will make the human body The loss of essential trace elements will also cause damage to the kidneys, and the side effects are relatively large, and lead-dispelling drugs have little significance in reversing the nerve damage caused by lead, so drugs are generally not used in clinical practice except for moderate to severe lead poisoning.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Example 1 Lead-removing traditional Chinese medicine composition

[0016] (1) The weight ratio of the API is as follows:

[0017] 50 grams of lemon peel, 50 grams of banyan leaves, 100 grams of loofah vine, 50 grams of sea sand, 100 grams of oxbaiteng, 50 grams of green peel.

[0018] (2) The preparation method is as follows:

[0019] 1. Get the crude drug according to the above-mentioned proportion by weight;

[0020] 2. Add lemon peel, ficus leaves, loofah vine, sea sand, oxbaiteng, green peel and soak in 8 times the total weight of water for 2 hours, heat to decoct, and filter after boiling; add 6 times the amount of water to the medicinal residue, heat to boiling, and filter after boiling , the filtrate is combined, that is, water decoction.

Embodiment 2

[0021] Example 2 Lead-removing traditional Chinese medicine composition

[0022] (1) The weight ratio of the API is as follows

[0023] 90 grams of lemon peel, 120 grams of banyan leaves, 150 grams of loofah vine, 90 grams of sea sand, 120 grams of oxbaiteng, 90 grams of green peel.

[0024] (2) The preparation method is as follows:

[0025] 1. Get the API according to the above proportion by weight;

[0026] 2. Add lemon peel, ficus leaves, loofah vine, sea sand, oxbaiteng, and green peel to soak in water for 3 hours, heat for decocting, and filter after boiling; add 7 times the amount of water to the dregs and heat to boiling. After filtering, the filtrates were combined to obtain a supernatant;

[0027] 3. When the supernatant is concentrated to a relative density of 1.06, it is fed into a spray dryer, the inlet air temperature is controlled at 150°C, the outlet air temperature is 105°C, and the feed rate is 5ml / min, to obtain 30 grams of spray-dried powder;

[0028] ...

Embodiment 3

[0029] Example 3 Traditional Chinese medicine composition for expelling lead

[0030] (1) The weight ratio of the API is as follows

[0031] 250 grams of lemon peel, 250 grams of banyan leaves, 300 grams of loofah vine, 200 grams of sea sand, 300 grams of oxbaiteng, 300 grams of green peel.

[0032] (2) The preparation method is as follows:

[0033] 1. Get the API according to the above proportion by weight;

[0034] 2. Add lemon peel, ficus leaves, loofah vine, sea sand, oxbaiteng, green peel and soak in water for 3 hours, heating and boiling, filter after boiling; add 8 times the amount of water to the dregs and heat to boiling. After filtering, the filtrates were combined to obtain a supernatant;

[0035] 3. When the supernatant is concentrated to a relative density of 1.06, it is fed into a spray dryer, the inlet air temperature is controlled at 150°C, the outlet air temperature is 105°C, and the feed rate is 5ml / min, to obtain 80 grams of spray-dried powder;

[0036...

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Abstract

The invention relates to a lead removing traditional Chinese medicine composition to solve the problem of rising of lead content in the body. The technical scheme is that the traditional Chinese medicine composition capable of promoting lead removing is made of the following raw materials according to weight: 5-25 parts of lemon peels, 5-25 parts of banian leaves, 10-30 parts of luffa stems, 5-20 parts of spora lygodii, 10-30 parts of hedyotis hedyotidea and 5-30 parts of green tangerine peels. The lead removing traditional Chinese medicine composition is low in production cost, small in toxic and side effect and obvious in blood lead, bone lead, liver lead and brain lead reducing effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition with the function of promoting lead excretion. Background technique [0002] Lead is a heavy metal widely used in industry. It has a strong affinity to tissues and can cause damage to multiple organs such as the liver and brain, especially the nervous system. It often causes peripheral neuritis, abnormal movement and sensation, etc. If lead enters the brain tissue with the blood stream, it will damage the cerebellum and cerebral cortex cells, interfere with metabolic activities, and cause insufficient supply of nutrients and oxygen, resulting in symptoms such as headache, memory loss, insomnia, and often accompanied by loss of appetite and gastroenteritis , abdominal pain and other digestive symptoms. Lead is ubiquitous in nature, and lead pollution in living environment and other life seriously endangers human h...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61P39/02
Inventor 蔡天革
Owner LIAONING UNIVERSITY
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