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Percutaneously implanted diffusion medicine deliver and method for manufacturing same

A manufacturing method and drug infusion technology, applied in the field of medical devices, can solve the problems of limited drug release period, diffusion time, and difficult control of concentration, and achieve the effect of ensuring long-term, simple structure, and stable implantation

Inactive Publication Date: 2014-04-23
GUANGZHOU MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drug sustained release period of this passive implantable drug carrier is limited, and the diffusion time and concentration are not easy to control

Method used

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  • Percutaneously implanted diffusion medicine deliver and method for manufacturing same
  • Percutaneously implanted diffusion medicine deliver and method for manufacturing same
  • Percutaneously implanted diffusion medicine deliver and method for manufacturing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Such as Figure 1~4 As shown, a percutaneously implanted diffusion drug delivery device includes a percutaneous implant 1 made of bioceramics. The percutaneous implant 1 is an "I"-shaped rotary body with a groove in the middle of the percutaneous implant 1. , the safety cap 2 is inserted into the groove of the percutaneous implant 1 to form a tight fit, the bottom of the percutaneous implant 1 is connected to one end of the drug delivery tube 3, and the other end of the drug delivery tube 3 is connected to the drug diffuser 4 made of porous bioceramics, and the drug delivery An anti-backflow device 5 is arranged inside the pipe 3 . The drug delivery tube 3 in this embodiment is made of flexible plastic such as medical silica gel. The drug diffuser 4 is made of uniform ultra-microporous porous bioceramics, which has proper permeability to drugs, but bacteria and viruses cannot pass through.

[0063] During specific use, the percutaneous implant 1 passes through the ski...

Embodiment 2

[0096]The difference between this embodiment and Embodiment 1 is that the middle position of the top of the “T”-shaped safety helmet of the safety helmet 2 is connected to the external drug delivery tube 6, which can realize periodic and continuous drug delivery.

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Abstract

The invention discloses a percutaneously implanted diffusion medicine deliver which comprises a percutaneous implant. The percutaneous implant is prepared from biological ceramics and is an 'H'-shaped rotator, a groove is arranged in the middle of the percutaneous implant, a safety cap is inserted into the groove to be in close fit with the groove, the bottom of the percutaneous implant is connected with one end of a medicine delivery tube, the other end of the medicine delivery tube is connected with a medicine diffuser prepared from porous biological ceramics, and a reflux preventing device is disposed inside the medicine delivery tube. The invention further provides a method for manufacturing the percutaneously implanted diffusion medicine deliver. The percutaneously implanted diffusion medicine deliver and the method have the advantages that shortcomings of limited sustained release period of medicines, difficulty in controlling diffusion time and concentration and the like in the prior art are overcome, the structure is simple, a liquid medicine can be diffused into a human body while bacteria and viruses cannot enter the human body, the percutaneous implant can be stably implanted in the human body assuredly for a long time, medicines can be locally administered intermittently or continuously from the outside of the human body, and the like.

Description

technical field [0001] The invention relates to medical device technology, in particular to a percutaneously implanted diffusion delivery device and a manufacturing method thereof. Background technique [0002] In clinical practice, there are many chronic and malignant diseases that require intermittent or continuous local administration of drugs to patients, such as local chemotherapy of tumors, pain relief, immune regulation, etc. In order to avoid gastrointestinal degradation and hepatic "first-pass effect", topical drug delivery has become an important means. The implantable drug delivery system (Implantable Drug Delivery System, IDDS) was first proposed by Lafarge in 1867. Its idea is to implant pills under the skin to obtain long-term sustained drug release. In 1937, Deansley and Parkes conducted animal research for the first time, implanting pills in the subcutaneous tissue, and the drug was released at a certain speed for a long time to maintain effective blood dru...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M37/00
Inventor 陈晓明阳范文
Owner GUANGZHOU MEDICAL UNIV
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