Retina three-dimensional imaging device based on double wavefront correctors for human eyes

Abstract

The invention provides a retina three-dimensional imaging device based on double wavefront correctors for human eyes. The device comprises an adaptive optical assembly, an eye ground monitoring imaging and sighting mark assembly, a confocal scanning assembly and an optical coherent chromatography assembly. The adaptive optical assembly comprises a wavefront sensor (27), the double wavefront correctors and a series of spherical reflectors. The double wavefront correctors are respectively a wavefront corrector (18) and a wavefront corrector (21). The wavefront sensor (27) receives reflected light reflected by the human eyes to conduct wavefront detecting to obtain low-order aberration and high-order aberration of the human eyes. After a computer (43) calculates the low-order aberration and the high-order aberration, and a high-voltage amplifier (42) is controlled to output voltage to control the double wavefront correctors to correct the low-order aberration and the high-order aberration of the human eyes. The retina three-dimensional imaging device adopts the double wavefront correctors to improve correcting capacity of the adaptive optical system on the aberrations of the human eyes. Simultaneously, high-resolution three-dimensional imaging of retinas of the human eyes is achieved.

Description

technical field [0001] The invention relates to an adaptive optics fundus imaging technology, which is a three-dimensional imaging device for the human eye retina based on a double wavefront corrector, and can be widely used for three-dimensional high-resolution imaging of the living human eye retina. Background technique [0002] Adaptive optics technology has the ability to correct dynamic wavefront aberrations in real time. Applying it to fundus retinal imaging technology can correct the aberrations of living human eyes that change randomly in time and space, so as to realize living human eyes close to the diffraction limit. Retinal high-resolution imaging. [0003] US patents 5,777,719, 5,949,521, 6,095,651, 6,379,005 B1, and 6,948,818 B2 introduce an adaptive optics retinal imaging system, which uses a Hartmann wavefront sensor to measure human eye aberrations, and uses a single wavefront corrector to correct the measured aberrations. This system uses a single discrete...

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Problems solved by technology

This system uses a single discrete deformable mirror as a wavefront corrector. The correction capability is limited, and it is difficult to meet the actual correction requirements for human eye aberrations.

Chinese patents CN1282564, CN1282565, CN1306796, CN1306797, and CN2728418 have introduced several other adaptive retinal imaging systems. Although new technologies and methods have been adopted to improve the imaging quality, the wavefront corrector has not been effectively improved. The ability to correct aberrations is still insufficient

Chinese patent ZL201010197028.0 introduces a reflective laser scanning ophthalmoscope system based on adaptive optics, which combines adaptive optics technology with laser scanning confocal ophthalmoscope technology to effectively improve the quality of retinal images. However, due to Only a single wavefront corrector is used for aberration correction and longitudinal tomography, and the insufficient stroke of the wavefront corrector results in low longitudinal spatial resolution of the image

[0004] Chinese patent CN10884524A combines adaptive optics technology and spectral domain optical coherence tomography technology, uses a single deformable mirror to realize real-time correction of human eye aberration, and obtains high-resolution three-dimensional imaging, but from the perspective of clinical application, this The aberration correction ability of the system is still insufficient for some groups of people. Its aberration correction ability is limited by the correction ability of a single deformable mirror. At the same time, there are some shortcomings in the lateral resolution of the image.

However, according to statistics, the aberrations of the human eye mainly include relatively large low-order aberrations and small high-order aberrations. 5D, the aberration correction range of the imaging system that only uses a single wavefront corrector is difficult to meet the aberration correction needs of different groups of people, and the residual aberration has a serious impact on the imaging resolution, which needs to be solved urgently

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