Detection system for colloidal gold immunochromatographic assay (GICA) test paper

Abstract

The invention discloses a detection system for colloidal gold immunochromatographic assay (GICA) test paper. The detection system comprises an information acquisition unit and an information processing / analysis unit connected with each other. The information acquisition unit is used for performing optical scanning on the test paper by emitting light beam to the test paper, receiving reflected beam from the test paper, converging the reflected beam and converting into electric signal. The information processing / analysis unit is used for processing / analyzing the electric signal and outputting detection result. The invention solves the technical problems in prior arts: only qualitative judgment and incapability of quantitative analysis by naked eye observation, and influence from subjective factor; ensures accurate and stable detection result; in comparison with CCD imaging technique, has small information processing computation amount that can be finished by ordinary singlechip; and adopts single LED as light source. The detection system has the advantages of low cost, high sensitivity, small volume, light weight, and portability.

Description

technical field [0001] The invention belongs to the technical field of medical detection, and in particular relates to a detection system for colloidal gold immunochromatography test paper. Background technique [0002] Colloidal gold immunochromatography test paper is a rapid diagnostic technology that has emerged in foreign countries in recent years. Its principle is to apply the rapid detection technology of colloidal gold to the antigen-antibody reaction, and fix the specific antibody on a certain zone of the nitrocellulose membrane first. , when one end of the dry nitrocellulose membrane is immersed in the sample, due to capillary action, the sample will move forward along the fiber membrane, and when it moves to the area where the antibody is fixed, the corresponding antigen in the sample will specifically bind to the antibody , through the color change of the reaction area to achieve specific immunodiagnosis. Colloidal gold immunochromatographic test paper has the ch...

AI Technical Summary

Problems solved by technology

In addition, when multiple LEDs work at the same time, the LED temperature rise will affect the stability of the light source, and the problem of LED heat dissipation needs to be considered

Considering these problems, the volume and weight of the instrument will increase significantly, and the portability of the equipment will be affected

Since white light LEDs are generally used as the light source, and the test zone of the colloidal gold immunochromatography test strip is magenta, which selectively absorbs green light, but the proportion of green light in white light is limited, so the test zone and the background The difference in reflected light is not obvious, and the color contrast between the area to be tested and the background is not high

Images