Selenium cyclic peptide and fatty acid mixture and preparation method thereof

Abstract

The invention discloses a selenium cyclic peptide and fatty acid mixture which is prepared from the traditional Chinese medicines of ginseng, radix rubiae, fructus lycii, fructus schisandrae chinensis, semen coicis, poria cocos, radix pseudostellariae, fructus gardeniae, selenium and the like by the modern microbial fermentation technology. The histone deacetylase all-natural synergic combined inhibitor with a brand-new chemical structure comprises the combined compounds such as selenium peptide, cyclic peptide, short-chain fatty acid and the like, and belongs to the tumor epigenetic regulation medicine of a novel anti-tumor action mechanism; and different from the traditional tumor treatment medicine, the selenium cyclic peptide and fatty acid mixture disclosed by the invention performs saturation attack by taking the abnormal epigenetic inheritance of tumor cells as a target spot, exerts an overall synergic anti-tumor effect by inducing the immunologic surveillance and immunity killing function of a patient, and is anti-oxidant and all-natural without chemical pollution.

Description

technical field [0001] The invention relates to a medicine "combination containing selenocyclic peptide and fatty acid" and a preparation method thereof, in particular to a selenocyclic peptide-fatty acid mixture with anti-tumor and anti-oxidation functions and a preparation method thereof. [0002] Background technique [0003] Tumor is a major and refractory disease that threatens human life and health, and human beings have experienced a long history of changes in the treatment of tumors. Anti-tumor drugs are one of the important treatment methods. With the deepening of research and the development of science and technology, anti-tumor drugs are constantly improving with the discovery of new targets. [0004] Scientists have found through in-depth studies on tumors that although the causes of tumor occurrence and development are very complex, they are all closely related to the abnormal activity of gene expression and gene expression products in the final analysis. At ...

AI Technical Summary

Problems solved by technology

However, new problems have emerged in the current research and development work: (1), the existing plant inhibitors have low content and poor effect; (2), the chemically synthesized inhibitors have single performance and poor effect; (3), most of the Inhibitors are easy to degrade in the body, have a short half-life, and are unstable; (4), the transcriptional inhibition of hematopoietic factors GATA-1 and 10 can cause adverse reactions such as thrombocytopenia; (5), and the trace element selenium has a positive anti-tumor function , but selenium ions precipitate in the neutral and alkaline environment of the small intestine, seriously affecting the effect