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Traditional Chinese medicine compound for curing schizophrenia

A technology of schizophrenia and composition, applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve problems such as extrapyramidal side effects, weight gain, etc., and achieve good therapeutic effect

Active Publication Date: 2012-11-14
西安市精神卫生中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although there are many types of drugs currently used to treat schizophrenia, western medicines that are effective are more or less accompanied by adverse reactions such as extrapyramidal side effects and weight gain.

Method used

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  • Traditional Chinese medicine compound for curing schizophrenia
  • Traditional Chinese medicine compound for curing schizophrenia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] In parts by mass, it includes the following components:

[0034] Gentiana 90g, Bupleurum 45g, Habitat 90g, Magnet 240g, Salvia 30g;

[0035] After mixing the above components, add water and decoct to make a decoction. Add 5000mL of water to the medicine, and fry to 1000mL. Take 50ml each time, 1-2 times a day.

Embodiment 2

[0037] Gentiana 90g, Bupleurum 45g, Habitat 90g, Magnet 240g, Salvia miltiorrhiza 30g, Fried jujube kernel 90g, Angelica dahurica 30g, Poria cocos 50g, Ding 30 parts, Yam 90g, Nutmeg 45g, Ligustrum lucidum 30g.

[0038] After mixing the above components, add water and decoct to make a decoction. Add 5000mL of water to the medicine, and fry to 1000mL. Take 50ml each time, 1-2 times a day.

Embodiment 3

[0040] 90 parts of gentian, 50 parts of Bupleurum, 90 parts of raw land, 240 parts of magnetic stone, 60 parts of salvia miltiorrhiza, 30 parts of tangerine peel, 20 parts of coix seed, 50 parts of Alisma.

[0041] Put the magnet in 5000mL water first, wait for the water to boil, mix the rest of the above components, and then add. Decoct to 1000mL. 50ml each time, 1-2 times a day.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine compound for curing schizophrenia, comprising the following bulk pharmaceutical chemicals in parts by weight: 1-90 parts of gentian, 1-50 parts of radix bupleuri, 1-90 parts of radix rehmanniae, 1-240 parts of magnet and 1-60 parts of Salvia miltiorrhiza. The compounds can be added or cut for adjusting according to practical conditions, and can be selected from any traditional Chinese medicine compound containing gentian, radix bupleuri, radix rehmanniae, magnet and Salvia miltiorrhiza. The compound can be adjusted through adding or removing the components according to practical conditions, and can be selected from any traditional Chinese medicinal compound comprising gentian, radix bupleuri, radix rehmanniae, magnet and Salvia miltiorrhiza or compound further with other added components or with the above removed components, preferably decoction of all the given bulk pharmaceutical chemicals, wherein the decoction can be obtained through a decocting method. Components adding and removing of the traditional Chinese medicine compound disclosed by the invention is similar to risperidone in effect. The traditional Chinese medicine compound has effects on the autonomic activities, space learning and memory improvement of a model rat. The mechanism may be related to the adjustment of DA, DOPA, HVA, 5-HT and 5-HIAA contents in the corpus striatum of the model rat.

Description

technical field [0001] The invention belongs to the technical field of schizophrenia treatment, and relates to a traditional Chinese medicine composition for treating schizophrenia. Background technique [0002] Schizophrenia, formerly known as praecox, is a psychiatric disease of unknown etiology. It usually occurs in young and middle-aged people, and there are often obstacles in perception, thinking, emotion, behavior and other aspects and incoordination of mental activities. Generally, there is no consciousness and mental retardation, and the course of the disease is more protracted. The disease is the most serious of all kinds of mental illness, with a prevalence rate of about 1% in the Chinese population and an annual incidence rate of about 0.1‰. In addition, the prevalence of schizophrenia in both urban and rural areas is negatively correlated with the family's economic level, that is, the average prevalence rate of residents with low economic levels is high, and th...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K36/8945A61K36/8964A61K36/8994A61K36/888A61P25/18A61K33/26
Inventor 师建国刘飞虎张燕田玉梅刘祥芹李炜东
Owner 西安市精神卫生中心
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