Application of Cistanche deserticola polysaccharide in medicine preparation used for improving learning memory function

A technology of Cistanche deserticola polysaccharides and learning and memory, applied in the application field of Cistanche deserticola polysaccharides in the preparation of drugs for improving learning and memory functions

Inactive Publication Date: 2012-10-24
INNER MONGOLIA MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the literature search did not find the application of Cistanche deserticola polysaccharides alone in improving learning and memory functions.

Method used

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  • Application of Cistanche deserticola polysaccharide in medicine preparation used for improving learning memory function
  • Application of Cistanche deserticola polysaccharide in medicine preparation used for improving learning memory function
  • Application of Cistanche deserticola polysaccharide in medicine preparation used for improving learning memory function

Examples

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Embodiment Construction

[0008] The animal experiments in which the Cistanche deserticola polysaccharides of the present invention are used to improve learning and memory functions are carried out according to the methods shown in the following implementation examples. The methods involved are technical means that can be grasped and used by those skilled in the art, but the following implementation examples shall not be construed as limiting the claims of the present invention in any sense.

[0009] Implementation example 1

[0010] Effects of cistanche deserticola polysaccharides on learning and memory acquisition impairment in mice induced by scopolamine hydrobromide, learning and memory reproducibility impairment in mice induced by ethanol, and learning and memory consolidation impairment in mice induced by sodium nitrite

[0011] (1) Materials and methods

[0012] 1 drug

[0013] Cistanche polysaccharide; Donepezil (Jiangsu Hansoh Pharmaceutical Co., Ltd. National Yao Zhunzi H20030472)

[0014]...

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Abstract

The invention discloses an application of Cistanche deserticola polysaccharide in medicine preparation used for improving learning memory function, and is characterized in that a channel water labyrinth and a Morris labyrinth are used for respectively discussing the influences of the mouse learning memory acquired obstacle caused by Cistanche deserticola polysaccharide on the scopolamine hydrobromide, the mouse learning memory reproducibility obstacle caused by ethanol and the mouse learning memory consolidation obstacle, which show that the Cistanche deserticola polysaccharide has intelligence promotion effect, and the application provided by the invention makes a research for a effect mechanism that the Cistanche deserticola polysaccharide improves the learning memory function to reduce the mouse hippocampus and cerebral cortex AChE active content and increase the content of Ach in brain.

Description

technical field [0001] The present invention relates to the application of Cistanche deserticola polysaccharide, in particular to the application of Cistanche deserticola polysaccharide in the preparation of medicines for improving learning and memory functions. Background technique [0002] Memory can be divided into four stages according to psychological characteristics and neurophysiological and biochemical mechanisms: memorization or acquisition, which refers to the process of leaving memory traces in the brain through learning; storage, consolidation and maintenance, both of which are after learning and training. The process in which the memory traces that occur are gradually transformed from a short-term unstable state to a long-term stable state and stored; reproduction refers to the process in which the memory traces stored in the brain are reproduced through recall or reproduction. Studies suggest that the central cholinergic system is closely related to learning an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P25/28
Inventor 李刚徐俊梅马慧武世奎
Owner INNER MONGOLIA MEDICAL COLLEGE
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