Panax notoginseng active ingredient-containing medicinal toothpaste and preparation method and application thereof
An active ingredient and toothpaste technology, which is applied in the field of pharmaceutical toothpaste containing the active ingredient of Panax notoginseng and its preparation field, can solve the problems of unsuitable long-term use, unreliable effect, insignificant effect and the like
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[0014] In the pharmaceutical toothpaste containing notoginseng active ingredient: the friction agent is one or more of calcium hydrogen phosphate dihydrate, hydrated silica, calcium carbonate, and aluminum hydroxide accounting for 25-60% by weight of the toothpaste; The agent is one or more of glycerin, propylene glycol, and sorbitol that account for 10 to 55% by weight of the toothpaste; the surfactant and foaming agent are sodium lauryl sulfate, sodium lauryl sulfate, and 1.5 to 2.5% by weight of the toothpaste. One or more of sodium lauroyl sarcosinate; the binder is sodium carboxymethyl cellulose, carboxyethyl cellulose, xanthan gum, guar gum, cara One or several kinds of gums; the stabilizer is tetrasodium pyrophosphate accounting for 1.5-3.0% by weight of the toothpaste; the balance is deionized water.
[0015] In the pharmaceutical toothpaste containing the active ingredient of notoginseng: the friction agent is calcium hydrogen phosphate dihydrate and / or 20% to 35% hyd...
Embodiment 1
[0027] Prepare materials according to the following proportions (percentage by weight): 0.4% of Panax notoginseng saponins, 0.5% of Panax notoginseng polysaccharide, friction agent is 25% hydrated silica, wetting agent is 15% glycerin and 35% sorbitol, surface active The agent and foaming agent are 2.5% sodium lauryl sulfate, the binder is 1% sodium carboxymethylcellulose and 0.4% xanthan gum, the stabilizer is 3.0% tetrasodium pyrophosphate, and the rest is 17.2% % deionized water. Take the total saponins of notoginseng, notoginseng polysaccharide, tetrasodium pyrophosphate, and deionized water in the preparation materials, put them into the water phase device, fully mix and dissolve for use; put the friction agent, wetting agent, surfactant and foaming agent, Adhesives are added to the mixture respectively, and at the same time, they are continuously stirred with a mixer at a speed of 1000r / min for 40min until fully mixed, ground and degassed to form a paste, and packaged. ...
Embodiment 2
[0029] Prepare materials according to the following ratio (percentage by weight): 0.1% of Panax notoginseng saponins, 0.2% of Panax notoginseng polysaccharide, friction agent is 40% calcium hydrogen phosphate dihydrate and 20% hydrated silica, wetting agent is 10% Glycerin and sorbitol 15%, surfactant and foaming agent 1.5% sodium lauryl sulfate, binder 0.5% sodium carboxymethyl cellulose and 0.3% xanthan gum, stabilizer 1.5 % tetrasodium pyrophosphate, and the rest is 10.9% deionized water. Take the total saponins of notoginseng, notoginseng polysaccharide, tetrasodium pyrophosphate, and deionized water in the preparation materials, put them into the premixing device, fully mix and dissolve for use; put the friction agent, wetting agent, surfactant and foaming agent, Adhesives are added to the mixture respectively, and at the same time, they are continuously stirred with a mixer at a speed of 1000r / min for 25 minutes until fully mixed, ground and degassed to form a paste, and...
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