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Ultrasound-enhanced bioreactor

A bioreactor, ultrasonic enhancement technology, applied in bioreactor/fermenter combination, specific-purpose bioreactor/fermenter, biochemical instruments, etc., can solve the patent unreported, ultrasonic bioreactor equipment development research blank and other problems to achieve the effect of speeding up the biological reaction rate, shortening the fermentation period, and improving mass transfer.

Active Publication Date: 2012-08-01
INST OF PROCESS ENG CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the field of traditional microbial fermentation and plant tissue culture, the development and research of corresponding ultrasonic bioreaction equipment is almost blank, and related patents have not yet been reported.

Method used

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  • Ultrasound-enhanced bioreactor
  • Ultrasound-enhanced bioreactor

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] After fermentation and inoculation, open the ultrasonic control interface, select to open all ultrasonic transducer groups, select ultrasonic frequency 40K, ultrasonic power 100%, set ultrasonic time for 10 minutes, perform ultrasonic enhancement, and exit the ultrasonic control interface after the ultrasonic effect is over.

Embodiment 2

[0036] At 2h, 6h, and 12h of the fermentation process, open the ultrasonic control interface, select to open all ultrasonic transducer groups, select ultrasonic frequency 28K, ultrasonic power 80%, set ultrasonic time for 5 minutes, perform ultrasonic enhancement, and wait for ultrasonic action Exit the ultrasound control interface after finishing.

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Abstract

The invention relates to an ultrasound-enhanced bioreactor, comprising a liquid state fermentation tank, an ultrasonic transducer, an ultrasonic generator and an ultrasonic fermentation control system, wherein the ultrasonic transducer is fixed on the side wall of the liquid state fermentation tank by bonding, the radiating surface of the ultrasonic transducer is fixed on the planar structure of the tank body of the liquid state fermentation tank by bonding. The ultrasonic fermentation control system comprises a biological fermentation process control unit and an ultrasonic control unit, wherein the biological fermentation process control unit is used for controlling the pH value, dissolved oxygen, temperature, rotating speed, air flow, tank pressure and supplementary material, and carrying out real-time monitoring on the whole fermentation process and conducting data recording and analysis; and the ultrasonic control unit is used for controlling the start of the ultrasonic transducer, the selection of ultrasonic frequencies, the selection of ultrasonic power and ultrasonic generation time in order to achieve optimum ultrasound-enhanced microbes and effects of growth metabolism of plant tissue cultures.

Description

technical field [0001] The invention relates to an ultrasonic-enhanced bioreactor, which uses ultrasonic waves to enhance liquid fermentation of microorganisms and liquid cultivation of plant tissues, improve dissolved oxygen and mass transfer, promote the growth of microorganisms and plant tissue cells, and increase the rate of biological reactions and the yield of metabolites. device. Background technique [0002] In the field of fermentation engineering, people continue to use the latest scientific research results of related disciplines to improve the fermentation process. The influence of some physical fields (such as light, electricity, heat, magnetism, etc.) on the biological characteristics of the fermentation process has been studied, and many achievements have been made. results. In recent years, due to the popularization and development of power ultrasonic equipment, the influence of ultrasonic on the fermentation process is attracting people's strong interest an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M3/00C12M1/42C12M1/36
CPCC12M29/08C12M23/20C12M35/04C12M27/00C12M27/24
Inventor 赵兵袁晓凡孔德柱王晓东
Owner INST OF PROCESS ENG CHINESE ACAD OF SCI
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