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Chinese medicinal composition for preventing and treating rheumatoid arthritis

A rheumatoid and composition technology, applied in the field of pharmaceutical inventions, can solve the problems of high price, limited wide application, and patients' inability to achieve curative effect, and achieve the effect of definite curative effect

Inactive Publication Date: 2012-07-04
INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the clinical application of existing drugs, many patients cannot achieve good curative effect, or cannot adhere to long-term medication due to side effects
In addition, in developing countries, the use of some effective biological products is limited, and some factors such as high prices limit their wide application

Method used

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  • Chinese medicinal composition for preventing and treating rheumatoid arthritis
  • Chinese medicinal composition for preventing and treating rheumatoid arthritis
  • Chinese medicinal composition for preventing and treating rheumatoid arthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Embodiment 1: Granules for preventing and treating rheumatoid arthritis

[0042] 1. Raw materials of traditional Chinese medicine: Paofuzi 10kg, Guizhi 12kg, Atractylodes macrocephala 15kg, Selaginella 9kg.

[0043] 2. Preparation method:

[0044] 1) Soak Guizhi, Atractylodes macrocephala, and Selaginella selaginella with water 8 times its weight for 30 minutes, and set aside;

[0045] 2) Put the aconite in a stainless steel decocting pot, add water 8 times its weight, first soak for 30 minutes, then decoct with a slow fire for 30 minutes, add the medicine and soaking liquid prepared in step 1), and decoct for 1.5 hours. Filter through a layer of gauze to collect the filtrate;

[0046] For the second time, add 6 times the water of the dregs and decoct for 1 hour, filter with four layers of gauze, combine the decoctions of the two decoctions, concentrate the filtrate to a relative density of 1.10 (30°C), then dry and pulverize to obtain the Chinese medicine extract. t...

Embodiment 2

[0048] Embodiment 2: Capsules for preventing and treating rheumatoid arthritis

[0049] 1. Raw materials of traditional Chinese medicine: Paofuzi 15kg, Guizhi 20kg, Atractylodes macrocephala 10kg, Selaginella 6kg.

[0050] 2, preparation method: with embodiment 1.

Embodiment 3

[0051] Embodiment 3: Injection for preventing and treating rheumatoid arthritis

[0052] 1. Raw materials of traditional Chinese medicine: Paofuzi 10kg, Guizhi 12kg, Atractylodes macrocephala 15kg, Selaginella 9kg.

[0053] 2. Preparation method: 1) Weigh the medicinal materials according to the proportion, then add 8 times the amount of 30% ethanol, extract under reflux for 2 hours, filter, and collect the filtrate;

[0054] 2) Step 1) the remaining medicinal residues were extracted with 5 times the amount of 30% ethanol under reflux for 1.5 hours, filtered, and the filtrate was collected;

[0055]3) Combine the filtrates of steps 1) and 2), recover ethanol under reduced pressure, concentrate in a water bath (60° C.) until the concentrated solution with a relative density of 1.03 is dried, and pulverized into fine powder to obtain the Chinese medicine extract.

[0056] 4) Dilute the Chinese medicine extract to 320mg / ml with water for injection, filter at 0.22um, and steriliz...

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Abstract

The invention discloses a Chinese medicinal composition for preventing and treating rheumatoid arthritis. The Chinese medicinal composition is prepared from the following Chinese medicines in part by weight: 5 to 20 parts of blast-fried prepared common monkshood daughter root, 5 to 30 parts of cassia twig, 5 to 30 parts of largehead atractylodes rhizome and 5 to 20 parts of honey-fired tamariskoid spikemoss herb. The invention also provides a preparation containing the Chinese medicinal composition and a preparation method for the preparation. Experiments prove that the Chinese medicinal composition has a definite curative effect of treating rheumatoid arthritis.

Description

technical field [0001] The invention relates to the field of medical inventions, in particular to a traditional Chinese medicine composition for preventing and treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis (rheumatoid arthritis, RA) is a chronic, systemic autoimmune system disease with unknown etiology, mainly involving joint destruction. The rate is higher than that of men, the ratio of men to women is about 1:3. The main pathological links include synovial inflammation and hyperplasia, pannus formation, and destruction of cartilage and bone tissue. Clinical studies have found that the degree of neovascularization in RA joints is positively correlated with the patient's condition, the degree of synovial hyperplasia and inflammatory cell infiltration, and drugs that inhibit angiogenesis can alleviate the condition of RA. [0003] At present, the commonly used clinical drugs for the treatment of rheumatoid...

Claims

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Application Information

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IPC IPC(8): A61K36/714A61P19/02A61P29/00
Inventor 林娜孔祥英刘春芳
Owner INST OF CHINESE MATERIA MEDICA CHINA ACAD OF CHINESE MEDICAL SCI
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