New biomarkers for assessing kidney diseases
A biomarker, kidney disease technology, used in disease diagnosis, biological testing, biomaterial analysis, etc., can solve the problem of not containing albumin
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[0090] Comparisons have been made between different stages of kidney disease, and also comparing diabetic nephropathy to other chronic kidney diseases.
[0091] General Information
[0092] Separate urine for six cohorts of diabetic patients with CKD stages 3-5 (officially stages 1-3 are all included here in the stage referred to as stage 3) and non-diabetic patients with CKD stages 3-5. (57) and plasma (76) samples were collected at the University Hospital of Montpellier. Targeted metabolomics was used to quantify approximately 320 metabolites from plasma, and 300 metabolites from urine, including the following classes: amino acids, biogenic amines, polyamines, acylcarnitines, phospholecithins , reduced mono- and oligosaccharides, sphingomyelin, eicosanoids, bile acids and intermediates of energy metabolism (as defined above), in the presence of isotopically labeled internal standards and detected by multiple reaction detection (MRM) FIA- and HPLC-tandem mass spectra were d...
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