Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Composition for preventing or treating irritable bowel syndrome

A technology for irritable bowel syndrome and composition, applied in the directions of drug combination, application, food science, etc., can solve problems such as no effect

Inactive Publication Date: 2012-05-02
SK CHEM CO LTD
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] So far, various Chinese herbal medicines (for example, Inula helenium, Poria cocas fungus, Angelica gigas, Paeonia japonica, Dioscorea japonica, Evodia officinalis, Citrus aurantium (trifoliate orange)) are beneficial in relieving IBS, but they did not show a significant effect in the CRD (colorectal dilation) model, a representative evaluation model of IBS

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Composition for preventing or treating irritable bowel syndrome
  • Composition for preventing or treating irritable bowel syndrome
  • Composition for preventing or treating irritable bowel syndrome

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0031]

[0032] Preparation of the ethanol-water solution extract of the Rhizome of Atractylodes officinalis. 100 g of the rhizome were dried in the shade and cut into slices. When performing reflux condensation extraction twice, 0.7 liter of 30, 50, 70 or 90 (v / v)% ethanol aqueous solution was added, and stirred for 4 hours. The extract is filtered, concentrated and dried. The final product was used in the following experiments.

[0033] Aqueous extracts of rhizomes of Atractylodes officinalis were prepared as follows: 100 g of rhizomes were added to a Chinese herbal medicine extractor (Daewoong Co., Model No. DWP5000M) and 1.5 liters of pure water was added thereto. Then turn on the first extraction switch for the first extraction for 150 minutes. Afterwards, the same amount of water was added, and the second extraction switch was turned on for a second extraction of 120 minutes. The extract is then filtered, concentrated and dried. The final product was used in the f...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention relates to a composition useful for preventing or treating irritable bowel syndrome, and to a method for treating or preventing irritable bowel syndrome. The present invention uses an Atractylodes japonica rhizome extract, preferably an Atractylodes japonica rhizome extract using an aqueous ethanol solution, and more preferably an Atractylodes japonica rhizome extract using an aqueous ethanol solution of 35 to 65 v / v%, as an active ingredient to treat or prevent irritable bowel syndrome. The atractylodes japonica extract exhibits superior effects of inhibiting bowel irritation and enhancement for dyschezia caused by stresses or irritable bowel.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating and preventing irritable bowel syndrome and its medical application. Background technique [0002] Irritable bowel syndrome (IBS) is a chronic disease without any detectable organic etiology accompanied by abdominal pain, abdominal discomfort such as persistent recurrent bloating, and excretion abnormalities such as diarrhea and constipation. Symptoms can be exacerbated by mental factors or stress. IBS is classified into diarrhea-type IBS, constipation-type IBS, or pain-type IBS, and the treatment of IBS is performed based on these symptoms. Among Korean IBS patients, 30.8% had diarrhea-type IBS, 24.6% had constipation-type IBS, and 44.6% had a stool state with alternating diarrhea and constipation. [0003] Medications used to treat IBS can be divided into those used to treat one symptom and those used to relieve symptoms overall. Drugs for treating abdominal pain include smooth mus...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/284A61P1/00A23L1/30A61P1/12
CPCA61K36/284A23V2002/00A23L1/3002A23L33/105A61P1/00A61P1/06A61P1/10A61P1/12A23V2200/3204A23V2250/21
Inventor 宣垣硕金泽洙金雄植琴道承柳根镐李海仁全孝镇闵东铣朴良惠孙玄株朴银珠李峰镛南宫好珍朴珉奭吴义喆
Owner SK CHEM CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com