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Chinese medicinal compositions for preventing and treating ventricular reconstruction due to coronary heart disease and use thereof

A ventricular remodeling and composition technology is applied in the application field of traditional Chinese medicine compositions in the preparation of ventricular remodeling drugs for prevention and treatment of coronary heart disease, and can solve the problems of complicated preparation process, insignificant ventricular remodeling effect, and many medicinal flavors, etc. Rich raw materials, no toxic side effects, and the effect of improving microcirculation

Inactive Publication Date: 2012-04-18
SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs still have the disadvantages of insignificant therapeutic effect on ventricular remodeling, too many medicinal flavors, and cumbersome preparation processes. Drugs with simple methods, but there are no reports about such drugs

Method used

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  • Chinese medicinal compositions for preventing and treating ventricular reconstruction due to coronary heart disease and use thereof
  • Chinese medicinal compositions for preventing and treating ventricular reconstruction due to coronary heart disease and use thereof
  • Chinese medicinal compositions for preventing and treating ventricular reconstruction due to coronary heart disease and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Preparation of Oral Solution of Ventricular Remodeling Drug 1 for Prevention and Treatment of Coronary Heart Disease (1)

[0025] Take 20 parts of astragalus, 4 parts of scorpion, and 4 parts of centipede, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

Embodiment 2

[0027] Preparation of Oral Liquid of Ventricular Remodeling Drug 1 for Prevention and Treatment of Coronary Heart Disease (2)

[0028] Take 40 parts of Astragalus membranaceus, 2 parts of scorpion, and 8 parts of centipede, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

Embodiment 3

[0030] Preparation of Oral Liquid of Ventricular Remodeling Drug 1 for Prevention and Treatment of Coronary Heart Disease (3)

[0031] Take 20 parts of Astragalus membranaceus, 4 parts of scorpion, and 8 parts of centipede, put them in a decoction container, add 5 times the amount of water to soak for 1 hour, boil for 30 minutes, and filter. Add 4 times the amount of water to the dregs and continue to decoct, boil for 20 minutes, and filter. The two filtrates were combined, concentrated on a water bath to a liquid medicine equivalent to 0.01g / ml of the original medicinal material, cooled and filled into sterilized medicine bottles, and placed in a 4°C refrigerator for later use.

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Abstract

The invention relates to use of Chinese medicinal compositions in preparation of medicines for preventing and treating ventricular reconstruction due to coronary heart disease. One Chinese medicinal composition is prepared from the following raw material medicines in part by weight: 20 to 40 parts of astragalus, 2 to 4 parts of scorpio and 4 to 8 parts of centipede. The Chinese medicinal composition has obvious effect on prevention and treatment of ventricular reconstruction due to coronary heart disease. The invention also relates to another Chinese medicinal composition which also comprises 9 to 15 parts of peach kernel, 10 to 20 parts of bitter orange and 40 to 70 parts of root of red-rooted salvia besides 20 to 40 parts of astragalus, 2 to 4 parts of scorpio and 4 to 8 parts of centipede. The components have qi-regulating, blood-activating and stasis-eliminating effects, so the treatment effect is improved; meanwhile, the Chinese medicinal composition medicines have wide application range and fewer side and toxic effects, fewer raw material components are needed, the raw materials are rich, the price is low, the preparation process is simple, and the Chinese medicinal compositions are suitable to be widely used.

Description

technical field [0001] The invention relates to the use of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of drugs for the prevention and treatment of coronary heart disease ventricular remodeling. Background technique [0002] Coronary heart disease is the most common heart disease, which refers to myocardial dysfunction and / or organic disease caused by coronary artery stenosis and insufficient blood supply, so it is also called ischemic heart disease. Symptoms are a crushing pain in the center of the chest cavity that can spread to the neck, jaw, arms, back, and stomach. Other possible symptoms of the attack include dizziness, shortness of breath, sweating, chills, nausea and fainting, and severe patients may die from heart failure. [0003] Coronary heart disease can cause ventricular remodeling, such as acute myocardial infarction and severe three-vessel coronary heart disease...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481A61K36/75A61P9/10A61K35/64A61K35/646A61K35/648
Inventor 董耀荣冯其茂邢建东周苗
Owner SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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