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Application of Chinese herbal medicine turmeric extraction in preparation of drug with lipase activity inhibition effect

An alcohol extract and activity inhibition technology, which is applied to the application field of the alcohol extract of Chinese herbal medicine turmeric in the preparation of medicines with lipase activity inhibitory effect, can solve the problem that Chinese herbal medicine cannot go to the world, the active ingredients of Chinese herbal medicine are unclear, and the pharmacological mechanism is unclear. question of clarity

Inactive Publication Date: 2013-07-10
BEIJING WBL PEKING UNIV BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to limitations such as unclear active ingredients and pharmacological mechanisms of Chinese herbal medicines, traditional Chinese herbal medicines cannot go to the world. So far, there is no weight-loss drug with independent intellectual property rights in my country.

Method used

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  • Application of Chinese herbal medicine turmeric extraction in preparation of drug with lipase activity inhibition effect
  • Application of Chinese herbal medicine turmeric extraction in preparation of drug with lipase activity inhibition effect
  • Application of Chinese herbal medicine turmeric extraction in preparation of drug with lipase activity inhibition effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Embodiment 1: the preparation of Scutellaria baicalensis water extract

[0061] Take Scutellaria baicalensis slices, prefabricate, pulverize; add 5 times the volume of deionized water, boil for 30 minutes, filter, and take the filtrate; use conventional methods to make conventional dosage forms for the preparation of lipase inhibitors.

Embodiment 2

[0062] Example 2: Preparation of Scutellariae Alcohol Extract

[0063] Scutellaria baicalensis slices are taken, prefabricated, and pulverized; 5 times the volume of 75% ethanol is added, ultrasonically extracted for 60 minutes, filtered, and the filtrate is obtained; conventional dosage forms are prepared by conventional methods for the preparation of lipase inhibitors.

Embodiment 3

[0064] Embodiment 3: the preparation of Pu'er tea water extract

[0065] Take Pu'er tea decoction pieces, prefabricate, pulverize; add 10 times the volume of deionized water, boil for 60 minutes, centrifuge at 4000r / min for 20 minutes, and take the supernatant; use conventional methods to make conventional dosage forms for the preparation of lipase inhibitors.

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Abstract

The invention discloses application of Chinese herbal medicine turmeric extraction in the preparation of a slimming and lipid-lowering drug or a drug with a lipase activity inhibition effect. The invention overcomes the defects of low efficiency and large side effect of the existing clinical slimming drugs, in particular traditional Chinese medicines and provides the slimming and lipid-lowering drug with clear mechanism, scientific target point, small side effect and high clinical efficiency.

Description

technical field [0001] The invention relates to the application of Chinese herbal medicine turmeric extract in the preparation of weight-loss and lipid-lowering medicine or the medicine with lipase activity inhibitory effect. Background technique [0002] Metabolic syndrome (MS) mainly includes risk factors such as obesity, impaired glucose tolerance, dyslipidemia, and hypertension. The incidence of diabetes (Diabetes mellitus, DM) and cardiovascular disease in MS patients is often several times that of the normal population. MS has seriously endangered human's physical and mental health and has become a worldwide public health problem, but so far our understanding of MS is very limited. Preliminary studies have confirmed that among many causes, obesity has a particularly close relationship with MS, and is a key factor and core link in the onset and development of MS. With the development of economy, the improvement of people's living standard and the change of lifestyle, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61K45/00A61P3/04A61P3/06
Inventor 段震文郭树仁闫雪秋
Owner BEIJING WBL PEKING UNIV BIOTECH
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