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Method for producing calculus bovis with natural quality

A natural and bezoar technology, applied in the field of preparation of bezoar, can solve the problems of low effective components, low yield of bezoar, and achieve the effects of enhancing memory, low price, and promoting hair regeneration

Inactive Publication Date: 2012-01-04
济南阿科普生物技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the 1970s, many scientific research institutions and scientific and technological workers in our country have invested in the research of "bezoar bezoar cultivation method in cattle", "bezoar bezoar cultivation method in vitro" and "chemical synthesis ratio method". There are still problems such as extremely low output and lower content of active ingredients than natural bezoar, such as: the artificial bezoar produced by the usual process can only produce about 10 grams of bezoar per 10 kg of bile... In a word, the current situation of artificial bezoar production is far from Far from meeting the needs of the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] One of the method that embodiment 1 makes natural quality Calculus Calculus

[0033] This embodiment is achieved through the following methods and steps:

[0034] 1. Add natural rosemary to the bile of the cow. When the specific gravity of the natural rosemary is 0.894 grams per liter of water, the weight ratio of the bile to the natural rosemary is 1000:1.8.

[0035] 2. Heat the bile in the above 1 to 80C°; then, remove the moisture by drying: the drying temperature is 100C°.

[0036] 3. Preparation of biological enzymes

[0037] The preparation method of this bacterium enzyme is:

[0038] A use beef extract and peptone medium to prepare Escherichia coli

[0039] Composition of ingredients: In 1kg of water, add beef extract 5, peptone 15g, Nacl 6-8g, agar 20g.

[0040] Specific preparation steps:

[0041] 1). Add beef extract, peptone and Nacl to the water, then heat and dissolve at 80°C;

[0042] 2). Put the agar into the above solution, and continue to heat an...

Embodiment 2

[0054] Embodiment 2 makes the method two of natural quality Calculus Calculus

[0055] This embodiment is achieved through the following methods and steps:

[0056] 1. Add natural rosemary to the bile of the cow. When the specific gravity of the natural rosemary is 0.912 grams per liter of water, the weight ratio of the bile to the natural rosemary is 1000:2.2.

[0057] 2. Heat the bile in the above 1 to 60C°; then, remove the moisture by drying: the drying temperature is 70C°.

[0058] 3. Preparation of biological enzymes

[0059] The preparation method of this bacterium enzyme is:

[0060] A use beef extract and peptone medium to prepare Escherichia coli

[0061] Composition of ingredients: In 1kg of water, add 8g of beef extract, 12g of peptone, 6-8g of Nacl, and 30g of agar.

[0062] Specific preparation steps:

[0063] 1). Add beef extract, peptone and Nacl to the water, then heat and dissolve at 70°C;

[0064] 2). Put the agar into the above dissolving solution, a...

Embodiment 3

[0076] Embodiment 3 makes the method three of natural quality Calculus Calculus

[0077] This embodiment is achieved through the following methods and steps:

[0078] 1. Add natural rosemary to the bile of the cow. When the specific gravity of natural rosemary is 0.9 gram of natural rosemary per liter of water, the weight ratio of bile to natural rosemary is 1000:2.

[0079] 2. Heat the bile in the above 1 to 70C°; then, remove the moisture by drying: drying temperature 90C

[0080] 3. Preparation of bacterial enzymes

[0081] The preparation method of this bacterium enzyme is:

[0082] A use beef extract and peptone medium to prepare Escherichia coli

[0083] Composition of ingredients: In 1kg of water, add 7g of beef extract, 14g of peptone, 6-8g of Nacl, and 25g of agar.

[0084] Specific preparation steps:

[0085] 1). Add beef extract, peptone and Nacl to the water, then heat and dissolve at 75°C;

[0086] 2). Put the agar into the above dissolving solution, and co...

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Abstract

The present invention discloses a method for producing calculus bovis with natural quality. The method comprises the following steps: adding natural rosemary to bile of domestic animal; heating the bile, then removing moisture through drying; preparing a biological enzyme, then adding the biological enzyme to the bile; carrying out precipitation treatment for the bile, and removing supernatant; drying the wet precipitate (calculus bovis) to obtain the calculus bovis product; carrying out warehousing for the product in 4 hours, wherein the product is stored under a shady and dried environment having a temperature less than 35 DEG C. With the present invention, the industrial preparation method for the calculus bovis with high yield and natural quality is provided; the insufficient supply of the calculus bovis for a long time is released, the benefit is provided for patients, and economic benefits of production enterprises are improved.

Description

technical field [0001] The invention relates to a method for preparing bezoar, in particular to a method for industrially producing natural quality bezoar. Background technique [0002] Natural bezoar is the dried gallstones of bovine animals, which are formed in the bile of cattle for several years. Calculus bezoar is an important animal medicinal material with definite functions and curative effects, and is widely used in traditional Chinese medicine formulas. According to statistics, there are more than 600 kinds of Chinese patent medicines containing bezoar ingredients. The State Drug Inspection Bureau stipulates that 42 kinds of famous and precious Chinese medicines such as Gongwan and Niuzihuang must be prepared with natural bezoar. According to reports, my country only produces 500-700 kg of natural bezoar per year, while the annual demand for bezoar in my country's pharmaceutical industry needs to consume at least 5,000 kg. Therefore, a large amount of bezoar has to...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/413
Inventor 王吉海李长鸿
Owner 济南阿科普生物技术开发有限公司
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