Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Gynecological Vaginal Acid Buffered Sterilizing Gel

A technology of bactericidal gel and vagina, applied in the field of gynecological vaginal gel preparations, can solve the problems of vaginal microecological flora imbalance, improper cleaning method, vaginal dryness and discomfort, etc., and achieves the promotion of estrogen secretion and the guarantee of quality uniformity , maintain vaginal moisturizing effect

Active Publication Date: 2011-12-07
石家庄诺利达医疗器械有限公司
View PDF4 Cites 13 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Under normal circumstances, the female vagina is acidic, which can inhibit the reproduction of pathogenic bacteria and has the ability of self-purification and antibacterial, but due to various reasons, 40% of them are due to improper cleaning methods, because many cleaning lotions are alkaline liquids, long-term use It will destroy the normal acidic environment of the vagina and cause the vaginal micro-ecological flora to be in an imbalanced state, causing vaginitis to become the most common disease in gynecology; the abuse or use of antibiotics will make bacteria resistant, and kill a large number of beneficial bacteria, destroying vaginal bacteria The balance of the swarm, resulting in the vigorous growth of fungi, and gynecological diseases are stubborn and difficult to cure
[0003] The suppositories or lotions currently used in the market may cause vaginal dryness and discomfort after use due to defects in formula and dosage form; the area of ​​action of the drug is limited to a certain position, and the vaginal folds cannot play a good role; suppositories still cannot be used after use Sufficiently absorbed leaving residue, etc.
[0004] Chinese patent application CN101773516A discloses a vaginal acidic buffer gel preparation and its preparation method and application. In the case of rampant bacteria, it cannot play a fundamental role

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Gynecological Vaginal Acid Buffered Sterilizing Gel
  • Gynecological Vaginal Acid Buffered Sterilizing Gel
  • Gynecological Vaginal Acid Buffered Sterilizing Gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] Take 2g of V80, 120g of glycerin, 10g of carbomer (940), 15g of polycarbophil, 2g of triethanolamine, 0.1g of vitamin E, 0.1g of mint, and 830g of water. First mix glycerin and water evenly, add V80 and stir evenly, then add carbomer (940) and polycarbophil and let stand for 6-8 hours, stir to fully dissolve, then add triethanolamine, stir to dissolve, and finally add vitamin E and mint can be fully stirred and dissolved, and packed in 3-5g syringes.

Embodiment 2

[0015] Take 2.5g of single- and double-chain compound quaternary ammonium salts, 124g of glycerin, 14g of carbomer (940), 18g of polycarbophil, 2.4g of triethanolamine, 0.25g of vitamin E, 0.25g of peppermint, and 835g of water. First mix glycerin and water evenly, add single and double chain compound quaternary ammonium salts and stir evenly, then add carbomer (940) and polycarbophil and let stand for 6-8 hours, stir to fully dissolve, then add triethanolamine, stir to dissolve , and finally add vitamin E and peppermint, fully stir to dissolve, and pack in 3-5g injectors.

Embodiment 3

[0017] Take 5g of single- and double-chain compound quaternary ammonium salts, 125g of glycerin, 15g of carbomer (940), 20g of polycarbophil, 3g of triethanolamine, 0.3g of vitamin E, 0.3g of peppermint, and 840g of water. First mix glycerin and water evenly, add single- and double-chain complex quaternary ammonium salts and stir evenly, then add carbomer (940) and polycarbophil and let stand for 6 to 8 hours, stir to fully dissolve, then add triethanolamine, stir Dissolve, and finally add vitamin E and peppermint, fully stir to dissolve, and pack in 3-5g injectors.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an acidic buffering sterilization gel for vagina gynaecologically. The gel consists of the following substances in parts by weight: 0.2-0.5 part of bactericide, 12-12.5 parts of glycerol, 83-84 parts of water, 1-1.5 parts of Carbomer, 1.5-2 parts of polycarbophil, 0.2-0.3 part of triethanolamine, 0.01-0.03 part of vitamin E, and 0.01-0.03 part of mint. The acidic bufferingsterilization gel has the advantages that: pathogenic bacteria can be quickly and effectively killed, inflammatory symptoms can be quickly and effectively relieved, normal pH value of the vagina is maintained, elasticity of the inner wall in the vagina can be kept, wetness of the vagina is maintained, and drug tolerance and drug resistance do not generate.

Description

technical field [0001] The invention relates to a gel preparation for gynecological vagina, in particular to an acid buffered sterilizing gel for gynecological vagina, which belongs to the field of medicine. Background technique [0002] Under normal circumstances, the female vagina is acidic, which can inhibit the reproduction of pathogenic bacteria and has the ability of self-purification and antibacterial, but due to various reasons, 40% of them are due to improper cleaning methods, because many cleaning lotions are alkaline liquids, long-term use It will destroy the normal acidic environment of the vagina and cause the vaginal micro-ecological flora to be in an imbalanced state, causing vaginitis to become the most common disease in gynecology; the abuse or use of antibiotics will make bacteria resistant, and kill a large number of beneficial bacteria, destroying vaginal bacteria The balance of the swarm will lead to the vigorous growth of fungi, and gynecological diseas...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K47/46A61K9/00A61P15/02A61K47/32
Inventor 李桂霞张建康任双军任晓华
Owner 石家庄诺利达医疗器械有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products