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Dentifrice Composition

A technology of composition and dentifrice, which is applied in the fields of medical science, dentistry, oral care, etc., can solve the problems of no inspiration, no disclosure of ascorbic acid ester, no disclosure of the proportion of the two components, etc., and achieve a good sense of use and a sense of inhibition Allergy and periodontal disease, excellent hyperesthesia suppression effect

Active Publication Date: 2011-11-30
LION CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this technology does not disclose the combined use of ascorbic acid ester or its salt, aluminum lactate and / or potassium nitrate, nor does it disclose the content ratio of the two components, and does not suggest the above-mentioned problem.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0071] Hereinafter, experimental examples, examples, and comparative examples are shown to specifically explain the present invention, but the present invention is not limited to the following examples. In addition, the mixing amount in the following examples is all mass %.

[0072] [Examples, Comparative Examples]

[0073] The dentifrice composition (toothpaste) of the composition shown in Table 1-Table 4 was prepared by the usual method, and the following experiment was performed and evaluation was performed. The results are shown in Tables 1-4.

[0074] The components used in the preparation of the dentifrice composition used magnesium ascorbic acid-2-phosphate (ascorbic acid PM, manufactured by Showa Denko Co., Ltd.) and sodium ascorbic acid-2-phosphate (STYI C-50, manufactured by DSM Nutrition Japan) , Ascorbic acid-2-sulfate (manufactured by ITO), aluminum lactate (manufactured by Musashino Chemical Research Institute), potassium nitrate (manufactured by Otsuka Chemical Co., ...

experiment example 1

[0075] [Experiment example 1] Evaluation of the improvement rate of bad breath due to periodontal disease

[0076] Ten volunteers with bad breath were used to evaluate the symptoms of hyperesthesia and the subjective symptoms of periodontal disease (swelling and bleeding of the gums). First, the subjects were asked to stop oral cleaning for 1 day, and 1L of exhalation was collected in a fluororesin collection container (Dura-Bassage N-type 1L size, manufactured by Sunplatec), and 10 perfumers evaluated the source according to the following criteria The level of bad breath of periodontal disease was scored as S1.

[0077] Next, use 1g of the tested dentifrice once a day, twice a day, use the usual method (brushing teeth with a toothbrush for 3 minutes) for 1 month, and stop the oral cleansing for 1 day, and put it in a fluororesin collection container (テドラ一 1L exhalation was collected from the Baba N-type 1L size, manufactured by Sunplatec Co., Ltd., and 10 perfumers evaluated the l...

experiment example 2

[0092] [Experimental example 2] Evaluation of usability

[0093] Using each toothpaste, 10 people with ivory hyperesthesia symptoms used 1g of the tested dentifrice at a time, using the usual method for 3 minutes (brushing the teeth with a toothbrush for 3 minutes), and evaluating the situation at this time by the following criteria The sensory feeling of use such as bitterness, etc., was averaged among 10 people. The average value is determined based on the determination criteria described later.

[0094]

[0095] 4: No bitterness is felt at all, and the feeling in use is very good.

[0096] 3: There is almost no bitterness, and there is no problem with the feeling in use.

[0097] 2: A weak bitterness is felt, and the feeling in use is slightly problematic.

[0098] 1: A strong bitterness is felt, and use cannot be tolerated.

[0099]

[0100] ◎: 3.5 points or more, 4 points or less

[0101] ○: 3 points or more, less than 3.5 points

[0102] △: 2 points or more, less than 3 points

[01...

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PUM

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Abstract

Disclosed is a dentifrice composition characterized by containing (A) at least one or more selected from ascorbic acid ester and salts thereof and (B) aluminum lactate and / or potassium nitrate, wherein the content ratio of ingredient (B) / ingredient (A) is 2-50 by mass ratio.

Description

Technical field [0001] The present invention relates to a dentifrice composition, which has excellent hyperesthesia inhibitory effects, exhibits a high preventive effect on bad breath and inflammation in the oral cavity derived from periodontal disease and a tartar removal effect, and has a good feeling of use. It is very effective for suppressing or preventing symptoms of hyperesthesia, bad breath, inflammation and other symptoms from periodontal disease. Background technique [0002] Periodontal disease is two major diseases in the oral cavity that are side by side with dental caries, and is a disease that causes approximately half of the cause of tooth loss. Most periodontal diseases are considered to be infections caused by bacteria mainly obligate anaerobic gram-negative bacilli. As a result, connective tissue and alveolar bone are destroyed. The clinical manifestations of this process include inflammation, swelling, bleeding, discharge of pus, bad breath, and gum atrophy. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/67A61K8/19A61K8/365A61Q11/00
CPCA61K8/676A61Q11/00A61K8/19A61K8/26A61K8/365
Inventor 寺林继乃近泽贵士天野步角谷治夫
Owner LION CORP
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