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Pharmaceutical composition for treating gout and preparation method thereof

A composition and drug technology, applied in the field of drugs, can solve the problems of many side effects, easy recurrence and the like

Inactive Publication Date: 2011-11-16
张金荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many medicines for the treatment of gout in Western medicine, there are disadvantages such as easy recurrence and many side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0009] Example 1: Schizonepetae 20g, Guizhi 20g, Caulis Caulis 20g, Feilongzhangxue 20g, Wisdom vine 20g, Rootless rattan 20g, Desmodium 20g, Poria cocos 20g, Curcuma 20g, Millae spatholobus 20g, Magnolia officinalis 20g, Phellodendron 15g, licorice 10g

[0010] Add water to decoct the above herbs for 3 times, 2 hours each time, add 8 times the amount of water each time, combine the decoction, filter, concentrate the filtrate, add ethanol until the alcohol content is 50%, let it stand for 24 hours, filter, The ethanol was recovered from the filtrate until it had no alcohol smell, concentrated, dried to obtain a dry paste, added starch, crushed, sieved, granulated with absolute ethanol, and granulated to obtain granules, orally, 5 g each time, 3 times a day.

Embodiment 2

[0011] Example 2: Schizonepetae 10g, Guizhi 10g, Caulis Caulis 10g, Flying Dragon’s Palm Blood 10g, Cengthia 10g, Rootless Vine 10g, Desmodium 10g, Poria cocos 10g, Curcuma 10g, Spatholobus 10g, Magnolia officinalis 10g, Phellodendron 5g, licorice 5g

[0012] Add water to decoct the above herbs for 4 times, 3 hours each time, add 8 times the amount of water each time, combine the decoction, filter, concentrate the filtrate, add ethanol until the alcohol content is 50%, let it stand for 36 hours, filter, The filtrate recovered ethanol until it had no alcohol smell, concentrated, dried under reduced pressure to obtain a dry paste, added starch, crushed, sieved, and pressed into tablets to obtain tablets.

Embodiment 3

[0013] Example 3: Schizonepeta 30g, Guizhi 30g, Caulis Caulis 30g, Feilongzhangxue 30g, Cane vine 30g, Rootless rattan 30g, Desmodium 30g, Poria cocos 30g, Curcuma 30g, Spatholobus 30g, Magnolia officinalis 30g, Phellodendron 25g, licorice 20g

[0014] For the above medicinal flavors, add water to decoct twice, 4 hours each time, add 8 times the amount of water each time, combine the decoction, filter, concentrate the filtrate, add ethanol until the alcohol content is 50%, let stand for 12 hours, filter , the filtrate recovered ethanol until it had no alcohol smell, concentrated, dried under reduced pressure, and molded into legal pills to obtain soft capsules.

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PUM

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Abstract

The invention relates to a pharmaceutical composition for treating gout and a preparation method thereof, belonging to the technical field of traditional Chinese medicine. The composition is prepared from medicinal materials such as fineleaf schizonepeta herb, cassia twig and the like, and has good effect.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method for treating gout, belonging to the technical field of medicines. technical background [0002] At present, with the improvement of people's quality of life and the improvement of diet structure, gout is showing a high-speed growth trend just like obesity, diabetes, and high blood pressure. Gout is more common in obese middle-aged men and mainly affects a single joint around it. The first attack is mostly in the first metatarsophalangeal joint, which is migratory, with sudden onset, joint redness and swelling, hot pain, and limited mobility. Recurrent episodes cause joint hypertrophy, deformity, and stiffness. Gouty nodules, also known as "tophi", are often formed in the auricle, bones near joints, tendon sheath cartilage, subcutaneous tissue, and kidneys. In the late stage, renal function declines significantly, and uremia occurs, which is life-threatening. Although ther...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P19/06
Inventor 张金荣
Owner 张金荣
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