Compound salinomycin preparation

A technology of compound salinomycin and salinomycin, which is applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of slow effect of traditional Chinese medicine and high anti-coccidial index and high anti-coccidial index.

Active Publication Date: 2013-04-17
SHANXI XINYUAN HUAKANG CHEM
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

By comparing the anti-coccidiostat efficacy of the western medicine Duqiu (1% maduramycin premix), it is found that the anti-coccidiostat index of the Chinese medicine powder is not as high as that of the western medicine Duqiu, which may be due to the slow effect of the traditional Chinese medicine for the sake of

Method used

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  • Compound salinomycin preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Take salinomycin, Qingzhu, Changshan and Diyu, respectively, and dry them at 50-90°C for 2 to 4 hours to completely dry them, place them in a ball mill to pulverize and pass through 80-120 mesh sieve. Weigh various APIs according to the proportions of 35% of salinomycin, 25% of Qingzhu, 25% of Changshan, and 15% of Sanyu, mix well, weigh and package to obtain compound salinomycin preparation.

Embodiment 2

[0017] Take salinomycin, Qingzhu, Changshan and Diyu, respectively, and dry them at 50-90°C for 2 to 4 hours to completely dry them, place them in a ball mill to pulverize and pass through 80-120 mesh sieve. Weigh various APIs according to the proportions of 25% salinomycin, 35% Qingzhu, 25% Changshan, and 15% Sanyu, mix them thoroughly, weigh, and package to obtain the compound salinomycin preparation.

Embodiment 3

[0019] Take salinomycin, Qingzhu, Changshan and Diyu, respectively, and dry them at 50-90°C for 2 to 4 hours to completely dry them, place them in a ball mill to pulverize and pass through 80-120 mesh sieve. Weigh various APIs according to the proportions of 30% salinomycin, 30% Qingzhu, 25% Changshan, and 15% Sanyu, mix well, weigh and package to obtain compound salinomycin preparation.

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Abstract

The invention discloses a compound salinomycin preparation, which is prepared by mixing 25-45 parts of salinomycin, 15-35 parts of sweet wormwood herb, 15-35 parts of antifebrile dichroa root and 5-25 parts of garden burnet root, and is used for the prevention and treatment of the coccidiosis in chickens. Through experimental verification, the ACI (Allowable Concentration Index) value of the compound salinomycin preparation ranges from 160.12 to 172.15, and the preparation is low in toxic or side effects, free of residue, and obvious in effect of resisting coccidiosis.

Description

Technical field [0001] The invention belongs to the technical field of medicines for livestock and poultry, and relates to a medicine for anti-coccidiosis, in particular to a compound salinomycin preparation used in combination with salinomycin and traditional Chinese medicine. Background technique [0002] Chicken coccidiosis is a protozoan disease that is caused by coccidia parasitizing intestinal epithelial cells, which seriously harms the chicken industry. In addition to the direct losses caused by morbidity and death, it can also lead to other losses such as lower feed returns and lower carcass quality. At present, the main method of preventing chicken coccidiosis is the application of antibiotics. However, due to the continuous emergence of drug-resistant strains, many chemicals lose their original effectiveness after 2 to 3 years of continuous application. The development of new coccidiosis chemicals is far Far from meeting the needs of the market. In addition, anticocci...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/35A61K36/739A61P33/02A61K31/351
Inventor 马爱民陶蕾
Owner SHANXI XINYUAN HUAKANG CHEM
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