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Cleaning-free medical ultrasonic couplant, and preparation method thereof

An ultrasonic couplant, wipe-free technology, applied in the direction of echo/ultrasonic imaging agent, etc., can solve the problems of easily polluted environment and need to wipe, and achieve the effect of avoiding cross infection, reducing dust, and improving cleaning and maintenance.

Inactive Publication Date: 2011-09-21
BEIJING DAOHANG ZHONGFU TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention is to solve the technical problems of wiping and easy to pollute the environment in the prior art, and provides a wiping-free medical ultrasonic coupling agent and its preparation method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] This example will illustrate an example of preparing 1000 g of the medical ultrasonic coupling agent of the present invention.

[0015] Product formula: Carbomer-934 1g, ethanol 50g, silk peptide (10% mass fraction concentration) 20g, povidone iodine 0.5g, deionized water 928.4g, citric acid (5% mass fraction concentration) 0.1g.

[0016] Wherein, the carbomer-934 as water-soluble macromolecular material accounts for 0.1% (being 1g) of raw material reagent gross mass; As the ethanol of volatile component accounts for 5% (being 50g) of raw material reagent gross mass; The silk peptide solution (10% mass fraction concentration) of protection component is 20g, and wherein silk peptide accounts for 0.2% (being 2g) of raw material reagent gross mass; As the polyvinylpyrrolidone iodine of sterilization component accounts for raw material reagent gross mass 0.05% (ie 0.5g); citric acid (5% mass fraction concentration) as a pH control component is 0.1g, and the rest is deionize...

Embodiment 2

[0024] Product formula: Carbomer-934 10g, ethanol 150g, silk peptide (10% mass fraction concentration) 100g, povidone iodine 20g, deionized water 719.9g, NaOH (5% mass fraction concentration) 0.1g.

[0025] Preparation method: Disperse Carbomer-934 in 100g deionized water, stir rapidly (800-1500 rpm) at 185°C to disperse evenly, then change to slow stirring (60-120 rpm), add Ethanol, add silk peptide solution, add chlorhexidine gluconate and the rest of water, continue to stir until the liquid is transparent, adjust the pH to 5.5-7.0 with NaOH, let stand to degas, and fill.

Embodiment 3

[0027] Product formula: carbomer-9345g, acetone 150g, hyaluronic acid (10% mass fraction concentration) 100g, chlorhexidine gluconate 20g, deionized water 714.9g, citric acid (5% mass fraction concentration) 0.1g.

[0028] Preparation method: Disperse Carbomer-934 in 100g deionized water, stir rapidly at 185°C to disperse evenly, then change to slow stirring, add acetone, add hyaluronic acid, add chlorhexidine gluconate and the rest of water, Continue to stir until the liquid is transparent, adjust the pH to 5.5-7.0 with citric acid, let stand to degas, and fill.

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Abstract

The invention discloses a cleaning-free medical ultrasonic couplant, and a preparation method thereof. The medical ultrasonic couplant comprises 0.1 to 2% by mass of water-soluble polymer materials, 5 to 30% by mass of volatile components, 0.2 to 2% by mass of skin moisturizing and protecting components, 0.05 to 5% by mass of sterilization components, a pH regulating component and deionized water. The medical ultrasonic couplant can form a thin film on patient skin and requires no cleaning, is safe for patient skin and does not contaminate clothes. Through utilizing the medical ultrasonic couplant, the advantages of simplifying ultrasonic detection processes, saving ultrasonic detection time, saving cleaning paper, reducing dust resulting from cleaning paper, and improving greatly an ultrasonic detection environment and the cleaning and maintenance of ultrasonic instruments. A viscosity of the medical ultrasonic couplant is controlled within a range of 3000 to 12000 centipoises and thus the medical ultrasonic couplant is a couplant with a medium to low viscosity and can be utilized by a spray way. Therefore, compared with the existing high viscosity couplant which is utilized by an extrusion way, the medical ultrasonic couplant provided by the invention is more convenient.

Description

technical field [0001] The invention relates to an ultrasonic medium used in medical ultrasonic testing, in particular to a wipe-free medical ultrasonic coupling agent and a preparation method thereof. Background technique [0002] Medical ultrasonic coupling agent is used for clinical ultrasonic diagnosis, it acts as a coupling between the transmitting probe and the measured object, so that the sound wave can enter the body smoothly to obtain a reliable image. The acoustic impedance of the tissue is close, the sound wave attenuation is small, clear images can be obtained, and there is no damage to the ultrasonic probe, it is easy to spread, and it is non-toxic and non-irritating to the human body. [0003] At present, the ultrasonic couplants used clinically are mainly high-viscosity transparent gels. After ultrasonic testing, it is necessary to wipe off the couplants on the patient's skin and the probe with toilet paper. On the one hand, the wiping of the coupling agent i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/22
Inventor 常才孙思遥杨斌
Owner BEIJING DAOHANG ZHONGFU TECH
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