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Syringe

A technology of syringes and nozzles, applied in the field of syringes, can solve the problems of splashing and expanding the degree of liquid medicine, and achieve the effect of easy avoidance and avoidance of wire drawing.

Active Publication Date: 2011-07-20
DENKA CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, even after the depressurized state in which the above-mentioned gap space K is opened by the top cover 103 being pulled out completely from the tip nozzle 101, as Figure 9 As exemplified in (a), it is also possible to produce such a thread that the liquid medicine extends from the tip nozzle 101 to the top cover 103
It is considered that this kind of threading tends to occur especially as the viscosity of the filling chemical solution 106 increases, and its degree tends to increase.
[0009] When such threading occurs, splashing of the liquid medicine after the threading breaks, adhesion of the liquid medicine to the clothes or hands of the medical-related person who handles the prefilled syringe, or tip nozzle after the threading breaks occurs. On the top opening 102 of 101, droplet Q1 generated due to surface tension is formed in a state exposed to the external space (refer to Figure 9 (b)) such undesirable situation

Method used

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Experimental program
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Effect test

Embodiment approach

[0052] In addition, the present invention is not limited to the above-described embodiments, but includes other various embodiments. That is, in the above-mentioned embodiment, the case where the luer lock portion 22 is provided on the distal end side of the syringe cylinder 2 and the top cap 6 has the outer cylinder cover portion 62 covering the luer lock portion 22 has been shown, but the present invention is not limited thereto. Alternatively, the syringe may be configured without the aforementioned Luer lock portion 22, and the cap may be configured without the aforementioned outer cylinder cap portion 62. This is because the gist of the present invention lies in the respective structures of the tip nozzle 21 and the cap sealing portion 63 in the above-described embodiment.

Embodiment

[0054] Using a prefilled syringe having the basic shape of this embodiment filled with a high-viscosity drug solution, various combinations of the hole diameter of the tip opening and the sealing length of the top cap sealing part were tested and confirmed. Is there any snagging when pulling out the top cover?

[0055] As the syringe 2, the entire length range e of the inner hole 212 tip side starting from the tip opening 211 (refer to Figure 4 ), making 7 types of syringes with aperture D of 1.5mm, 1.3mm, 1.0mm, 0.7mm, 0.6mm, 0.5mm, and 0.4mm. On the other hand, as the top cap 6 , five kinds of top caps of 8.0 mm, 6.0 mm, 4.5 mm, 3.0 mm, and 2.0 mm in length S of the sealing portion of the top cap sealing portion 63 were manufactured.

[0056] The number of combinations of the hole diameter D and the length S of the sealing part is 7 (types) × 5 (types), that is, 35 types. Therefore, according to the 35 combinations, prepare 10 samples for each type, and fill them with B-type...

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Abstract

The present invention provides a syringe which prevents a medication liquid filled into the syringe from forming strands from the tip nozzle when removing the cap, even in cases when the medication liquid is highly viscous. A tip opening (211) is closed by causing the inner peripheral surface (631) of the cap sealing part (63) of a cap (6) to be in close contact with the outer peripheral surface (214) of the tip portion of the tip nozzle (21) of a barrel (2). At the same time, the outer periphery of a Luer lock section (22) is covered with the outer tube cover (62) of the cap. A swollen section (213) is provided to the front end portion of the inner hole (212) in the tip nozzle to reduce the diameter (d) of the tip opening. The length (s) of the seal formed by the cap sealing part (63) is set to a predetermined level which is relatively short. The diameter of the medication liquid placed in the syringe and sucked until the liquid is destroyed by a vacuum when the cap is removed is set to a very fine diameter and is adapted so as to be quickly destroyed by a vacuum. Thus, even if the medication liquid filled into the syringe is highly viscous, the medication liquid does not form strings.

Description

technical field [0001] The present invention relates to a syringe, in particular to a syringe used for a syringe (pre-filled syringe: Pre-filled syringe) that has been filled with a medical solution. The prefilled syringe is shipped with a cap attached to the nozzle at the tip of the syringe in a state where the drug solution inside is sealed. In particular, the present invention relates to a syringe that eliminates the possibility of threading from the tip nozzle during actual use after shipment as a prefilled syringe. Background technique [0002] Generally, in a prefilled syringe, the filling drug solution inside is in a sealed state between a gasket fitted in from the base end opening of the syringe for the prefilled syringe and a cap attached to the tip nozzle. Then, the prefilled syringe filled with the drug solution in a hermetically sealed state is shipped after being sterilized and provided to medical institutions and the like. [0003] When heat sterilization is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M5/28A61M5/31
CPCA61M2005/3104A61M2005/3139A61M5/28A61M5/24A61M5/31
Inventor 多幡恒太香坂昌信日置和利松本一平朝日德彦
Owner DENKA CO LTD
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