Compound elder composition for treating bone injury and preparation method and pharmaceutical application thereof

Abstract

The invention relates to a compound elder composition and a preparation method and pharmaceutical application thereof. The composition can be used for treating diseases such as bone injury and the like. The preparation method of the Chinese medicinal composition comprises the following steps of: performing heating reflux extraction on the root and the skin of elder by using 95 percent ethanol to obtain ethanol extract, suspending in water, adsorbing by using AB-8 macroporous resin, eluting by using the water, 10 percent ethanol and the 95 percent ethanol respectively, concentrating 10 percentethanol eluent and drying to obtain active ingredient extract of the elder; decocting twotooth achyranthes root in the water to obtain extract, suspending in the water, adsorbing by using D101 macroporous resin, eluting by using the water, 50 percent ethanol and the 95 percent ethanol respectively, concentrating 50 percent ethanol eluent and drying to obtain active ingredient extract of the twotooth achyranthes root; and mixing the active ingredient extract of the elder and the active ingredient extract of the twotooth achyranthes root in a ratio to prepare capsules, tablets, granules, pills,oral liquid, injection or external preparations.

Description

technical field [0001] The invention relates to a composition, in particular to a traditional Chinese medicine composition for treating bone damage. The composition is composed of active ingredient extracts of elderberry and achyranthes bidentata, and can be used for treating bone damage. Background technique [0002] Bone injury is a common clinical disease, mainly including: fracture, osteoporosis, etc. Various forms of bone injury are clinically high incidence. At present, there are many clinical methods for treating bone injuries, most of which are surgery or external fixation, combined with drug therapy. The bone injury takes a long time to heal, the patient suffers a lot, and there are still many unsatisfactory parts in the treatment effect. Taking fractures as an example, the symptoms are: long course of treatment, great pain, large callus at the fracture site, malunion at the fracture site to varying degrees, late functional exercise, slow growth of callus, and some...

AI Technical Summary

Problems solved by technology

It not only brings great pain to the patient physically and mentally, but also creates a lot of pressure and burden on the family and society.

Now there are many medicines for treating bone injury diseases. Western medicines are often simple in composition and act on a certain aspect of anti-inflammation, analgesia or promotion of bone healing in bone injuries. Most of the traditional Chinese medicine preparations used in clinical practice have many flavors, insignificant curative effect, rough preparations, difficult quality control, poor drug stability, etc., so that they cannot be used in clinical practice for a long time. in a state of relative lack

Elderberry and Achyranthes bidentata both come from traditional Chinese medicine, and are mostly used in the treatment of bone injuries in clinical practice. The compatibility of the two can play a synergistic effect, and comprehensively improve various indications of bone injuries in multiple ways and links. The composition of the two active ingredients It has not been reported for the treatment of bone injuries

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