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Traditional Chinese medicine fructus sophorae suppository for treating hemorrhoid hematochezia and preparation method thereof

A technology for hemorrhoids with blood in the stool and angular suppository is applied in the field of Chinese patent medicine preparation to achieve the effects of avoiding toxic and side effects, high safety and small toxic and side effects

Active Publication Date: 2012-07-11
SHANXI ZHENDONG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a Chinese medicine Huaijiao suppository for treating hemorrhoids with blood in the stool and its preparation method which is safe, reliable, definite in curative effect, convenient to use, less in toxic and side effects, and easy to be accepted by consumers, so as to solve the problems existing in the existing Huaijiao pill traditional preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] a. Take 250g fried Sophora japonica, 130g Burnet charcoal, 100g Scutellaria baicalensis, 100g angelica, 100g fried Fructus Aurantii, 75g Fangfeng, add 8 times the amount of 70% ethanol solution to reflux extraction for 3 times, each time for 3 hours, and combine the extracts , filtered, the filtrate was concentrated under reduced pressure at 60°C to form an extract, added 10 times the amount of 80% ethanol solution, stirred, allowed to stand, filtered, and the filtrate was recovered under reduced pressure at 60°C until there was no alcohol smell, and reduced pressure at 60°C Concentrate, dry in an oven at 70°C until the water content of the dry extract is 5%, crush and pass through a 100-mesh sieve to obtain the extract.

[0020] b. Take 700 g of semi-synthetic fatty acid glyceride, heat and melt in a water bath at 75°C, add the dry powder of the above extract and mix well to obtain a suspension to be filled.

[0021] c. Put the suspension in a homogenizer, disperse eve...

Embodiment 2

[0023] a. Take 280g fried Sophora japonica, 110g Burnet charcoal, 90g Scutellaria baicalensis, 90g Angelica sinensis, 90g fried Fructus Aurantii, 70g Fangfeng, add 10 times the amount of 60% ethanol to reflux and extract 3 times, each time for 3 hours, combine the extracts, filter , the filtrate was concentrated under reduced pressure at 60°C to form an extract, added 8 times the amount of 80% ethanol solution, stirred, left to stand, filtered, and the filtrate was recovered under reduced pressure at 60°C until there was no alcohol smell and concentrated under reduced pressure at 60°C, 70 Drying in an oven at ℃, the moisture content of the dry extract is 5%, and crushing through a 100-mesh sieve to obtain the extract.

[0024] b. Take 850 g of semi-synthetic fatty acid glycerides, heat and melt in a water bath at 75°C, add the dry powder of the above extract and mix thoroughly to obtain a suspension to be filled.

[0025] c. Put the suspension in a homogenizer, homogenize and ...

Embodiment 3

[0027] a. Take 220g fried Sophora japonica, 130g Burnet charcoal, 85g Scutellaria baicalensis, 85g Angelica sinensis, 85g fried Fructus Aurantii, 85g Fangfeng, add 6 times the amount of 70% ethanol to reflux and extract 3 times, each time for 3 hours, combine the extracts, filter , the filtrate is concentrated under reduced pressure at 60°C to form an extract, add 10 times the amount of 80% ethanol solution, stir, stand still, filter, and recover the ethanol under reduced pressure at 60°C until the filtrate has no alcohol smell and concentrate under reduced pressure at 60°C, 70 Drying in an oven at ℃, the moisture content of the dry extract is 5%, and crushing through a 100-mesh sieve to obtain the extract.

[0028] b. Take 700 g of semi-synthetic fatty acid glyceride, heat and melt in a water bath at 75°C, add the dry powder of the above extract and mix well to obtain a suspension to be filled.

[0029] c. Put the suspension in a homogenizer, homogenize and disperse evenly at...

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PUM

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Abstract

The invention discloses traditional Chinese medicine fructus sophorae suppository for treating the hemorrhoid hematochezia, which is prepared by mixing 650-900 parts of suppository base with alcohol extracts as medicinal active ingredients, wherein the alcohol extracts are prepared from stir-baked fructus sophorae, charred radix sanguisorbae, baikal skullcap root, stir-baked fruit of trifoliate orange, angelica and divaricate saposhnikovia root. The fructus sophorae suppository disclosed by the invention is modern novel traditional Chinese medicine preparation prepared by the prescription of the traditional fructus sophorae pill preparation, and has the effects of clearing intestine and dispelling wind, and dispelling heat from blood and stopping bleeding. The traditional Chinese medicinefructus sophorae suppository has local functions, mainly has the effects of lubrication, antibiosis, inflammation diminishing, itching relieving and the like and is convenient to use, nonirritant, easy to be accepted by sufferers. In addition, the traditional Chinese medicine fructus sophorae suppository can be further absorbed by chamber mucous membranes to join the blood circulation so as to realize the general action, such as analgesia, stimulation and the like; furthermore, the traditional Chinese medicine fructus sophorae suppository can not be subjected to enterohepatic circulation, thefirst pass effect of medicines is avoided, and the toxic or side effect of the medicines on the liver is also avoided.

Description

technical field [0001] The invention belongs to the technical field of preparation of Chinese patent medicines, and relates to a traditional Chinese medicine Huaijiao suppository for treating hemorrhoids with blood in the stool and a preparation method of the suppository. Background technique [0002] Hemorrhoids with blood in the stool are clinically common diseases and frequently-occurring diseases. According to the theory of traditional Chinese medicine, hemorrhoids can be divided into external hemorrhoids, internal hemorrhoids, and mixed hemorrhoids according to the position of hemorrhoids. The cause of the disease is that heat forces the blood to descend, and stagnation persists. Old age and infirmity, drinking and smoking, spicy food, etc. are all predisposing factors. The clinical manifestations of hemorrhoids are anal itching, swelling and pain, and bleeding. According to relevant census data, the incidence rate of anorectal diseases is 59.1%, and hemorrhoids acco...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K9/02A61P9/14A61P7/04A61P1/00
Inventor 李安平董迷柱菅晓勇李建伟武勇王军霖刘近荣
Owner SHANXI ZHENDONG PHARMA
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