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Application of triclosan to resistance to Eimeria tenella

A technology of Eimeria and triclosan, which is applied in the field of triclosan, can solve the problems that the anti-Eimeria tenella cannot be inferred, and the anti-Eimeria tenella of triclosan has not been seen yet.

Inactive Publication Date: 2011-04-27
广东省农业科学院兽医研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] So far, there has been no report on the effect of triclosan on Eimeria tenella, and it is impossible to infer whether it has an anti-Eimeria tenacia effect based on the known properties of triclosan

Method used

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  • Application of triclosan to resistance to Eimeria tenella
  • Application of triclosan to resistance to Eimeria tenella
  • Application of triclosan to resistance to Eimeria tenella

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0031] Preparation of powder: take 25g of triclosan (content not less than 99%) and 75g of starch and mix evenly. Usage and dosage: 12.5 grams of triclosan is mixed in every 100 kilograms of feed, and fed according to the daily food intake.

example 2

[0033] Preparation of suspending agent: take 25g of triclosan (content not less than 99%), add dimethyl sulfoxide and stir, and dissolve to 100ml.

[0034] Usage and dosage: the suspension agent is mixed in drinking water so that the concentration of triclosan is 6.25g / 100Kg water, and then drink water according to the daily drinking water amount.

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Abstract

The invention discloses application of triclosan to preparation of medicaments for resisting Eimeria tenella. The triclosan and pharmaceutically acceptable accessories are uniformly mixed and the mixture is added into water or feeds. Animal infection experiments prove that the anticoccidial index (ACI) of the triclosan reaches over 177.9, and the triclosan has better effect of resisting Eimeria tenella.

Description

technical field [0001] The invention relates to a new application of triclosan, in particular to the application of triclosan in resisting Eimeria tenella. Background technique [0002] Chicken coccidiosis is the most important disease that seriously endangers the intensive chicken industry production, and the economic loss caused by it is as high as more than 2.5 billion pounds every year. The most harmful is Eimeria tenella. Although my country has no accurate statistics on this so far, the most conservative estimate is that the loss should not be less than 2.5 billion RMB. Chemical drug treatment is one of the important measures to control coccidiosis in chickens, but at present chicken coccidiosis has extensive and serious drug resistance, and new anticoccidiosis drugs are urgently needed to be put on the market. [0003] Triclosan (Triclosan), chemical name, 2,4,4'-trichloro-2'-hydroxydiphenyl ether, also known as Triclosan, Yujie pure MP (Irgacare MP), Yujie new DP-3...

Claims

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Application Information

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IPC IPC(8): A61K31/085A61P33/02
Inventor 孙铭飞蔡建平谢明权覃宗华吕敏娜袁建丰李祥瑞吴彩艳王志军余劲术
Owner 广东省农业科学院兽医研究所
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