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Specimen preserving, fixing and accelerating agent

An accelerant and specimen technology, applied in botany equipment and methods, preservation of human or animal bodies, plant preservation, etc., can solve the problems of inconvenient use and long fixation time in hospital pathology departments, and reduce the time spent in fixation , the effect of shortening the fixed time

Active Publication Date: 2011-03-16
无锡市江原实业技贸有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The environment-friendly non-formalin fixative adopts the natural sedimentation fixation mechanism, and the penetration rate in tissue specimens is lower than that of formalin, resulting in a longer fixation time than formalin, which brings inconvenience to the wide use of hospital pathology departments

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The anticorrosion and fixation accelerator of the specimen consists of 2% laurocapram, 0.2% disodium ethylenediaminetetraacetic acid (EDTA-2Na), and the rest is an ethanol solution with a concentration of 50vt%. In the tissue specimen fixation test, the fixation speed was 5 mm / 10 hours without adding the specimen fixation accelerator, and was 5.6 mm / 10 hours after adding the specimen fixation accelerator, and the fixation speed was increased by 12%.

Embodiment 2

[0026] The weight percent of the specimen antiseptic fixation accelerator is composed of laurocapram 10, disodium edetate-2Na (EDTA-2Na) 5%, and the rest is an ethanol solution with a concentration of 50vt%. For the tissue specimen fixation test, the fixation speed was 5 mm / 10 hours without adding the specimen fixation accelerator, and 6.5 mm / 10 hours after adding the specimen fixation accelerator, and the fixation speed was increased by 30%.

Embodiment 3

[0028] The weight percent of the specimen antiseptic fixation accelerator consists of 5% thilone, 0.2% ethylenediaminetetraacetic acid tetrasodium salt (EDTA-4Na), and the rest is an ethanol solution with a concentration of 50vt%. In the tissue specimen fixation test, the fixation speed was 5mm / 10 hours without adding the specimen fixation accelerator, and was 5.7mm / 10 hours after adding the specimen fixation accelerator, and the fixation speed was increased by 14%.

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PUM

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Abstract

The invention discloses a specimen preserving, fixing and accelerating agent which comprises the following components in percentage by weight: 2-20% of main additive, 0.2-5% of auxiliary additive and the balance of ethanol solution of which the concentration is 50vt%, wherein the main additive is selected from laurocapram, thiazone, menthol or isopropyl myristate; and the auxiliary additive is selected from disodium ethylene diamine tetraacetate, ethylene diamine tetraacetic acid tetrasodium salt, ethylene diamine tetraacetic acid dipotassium salt, ethylene diamine tetraacetic acid tripotassium salt, ethylene diamine tetraacetic acid calcium disodium salt or ethylene diamine tetraacetic acid zinc disodium salt. The specimen preserving, fixing and accelerating agent can effectively improvethe velocity of permeability of an environment-friendly non-formalin fixing solution in human bodies, animals and plant tissues, shorten the fixing time, and improve the efficiency and the quality for manufacturing pathological sections by a pathology department.

Description

technical field [0001] The invention relates to the technical field of anticorrosion, in particular to a specimen anticorrosion fixation accelerator. Background technique [0002] Formalin (formalin, diluted formaldehyde solution) is the most commonly used preservative for human, animal, and plant tissue specimens. Formaldehyde in formalin can combine with the amino groups of proteins, and the proteins undergo irreversible denaturation. It is used in human, animal, and plant tissues. The preservation of tissue specimens has a history of more than one hundred years. In the pathology department and surgical operating room of the hospital, formalin is used to fix pathological tissue specimens to prevent tissue autolysis, structural damage, and cell deformation. pathological diagnosis. Medical pathological diagnosis requires high-quality pathological sections, and correct specimen fixation is the first step in making high-quality sections. [0003] Formalin is highly toxic an...

Claims

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Application Information

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IPC IPC(8): A01N1/00A01N3/00
Inventor 谢敏浩吴军戴军邹霈刘娅灵何拥军王洪勇吴昊
Owner 无锡市江原实业技贸有限公司
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