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Aerosol for preventing and controlling pullorum disease and preparation method thereof

A technology for chicken pullorum and aerosol, which is applied in the field of preparation of the aerosol, can solve the problems of easy generation of drug resistance, poor treatment effect, drug residue and the like, and achieves the effects of not easy drug resistance and convenient medication.

Inactive Publication Date: 2011-01-19
ZHENGZHOU HOUYI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide an aerosol for preventing and treating pullorum in chickens, so as to solve the problems that drug resistance is easily produced when antibiotics are used to treat pullorum in chickens, drugs remain in the chicken body, and the treatment effect is poor.

Method used

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  • Aerosol for preventing and controlling pullorum disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A, a kind of consumption of each raw material of the aerosol that is used to prevent and treat chick pullorum is:

[0023] The aerosol is made of the following raw materials: Coptidis 180g, Phellodendron 160g, Rhubarb 70g, Radix Radix 130g, Licorice 60g, Scutellaria baicalensis 100g, and propellant 10g, wherein the propellant is difluorodichloromethane and propylene glycol 100ml, ethanol 180ml, water: balance.

[0024] B, the preparation method is as follows:

[0025] 1) Weigh 180 grams of Coptis chinensis, 160 grams of Cortex Phellodendri, 70 grams of rhubarb, 130 grams of Radix Isatidis, and 60 grams of licorice, add 9 times the total weight of 5 traditional Chinese medicines in water, decoct three times, the first time for 2 hours, and the next two times each for 1.5 h, combining three decoctions, filtering, and concentrating the filtrate to obtain extract A of five kinds of traditional Chinese medicines;

[0026] 2) Weigh 100 grams of Scutellaria baicalensis, add ...

Embodiment 2

[0031] A, a kind of consumption of each raw material of the aerosol that is used to prevent and treat chick pullorum is:

[0032] The aerosol is made of the following raw materials: Coptidis 60g, Phellodendron 100g, Rhubarb 55g, Radix Radix 180g, Licorice 50g, Scutellaria baicalensis 170g, and propellant 18g, of which the propellant is liquefied butane gas and propylene glycol 50ml , ethanol 100ml, water: balance.

[0033] B, the preparation method is as follows:

[0034] 1) Weigh 60 grams of Coptis chinensis, 100 grams of Phellodendron Phellodendri, 55 grams of rhubarb, 180 grams of Radix Radix, and 50 grams of licorice, add water 8 times the total weight of 5 traditional Chinese medicines, and decoct three times, the first time for 2 hours, and the next two times Each was decocted for 1.5 hours, combined three decoctions, filtered, and the filtrate was concentrated to obtain extract A of five kinds of traditional Chinese medicines;

[0035] 2) Weigh 170 grams of Scutellari...

Embodiment 3

[0040] A, a kind of consumption of each raw material of the aerosol that is used to prevent and treat chicken pullorum is:

[0041] This aerosol is made of the following raw materials: Coptidis 90g, Phellodendron 55g, Rhubarb 100g, Radix Radix 60g, Licorice 90g, Scutellaria baicalensis 60g, propellant 30g, wherein the propellant is trichlorofluoromethane and dichloromethane A total of 30 grams of chlorotetrafluoroethane, 150 ml of propylene glycol, 300 ml of ethanol, water: the balance.

[0042] B, the preparation method is as follows:

[0043] 1) Weigh 90 grams of Coptis chinensis, 55 grams of Cortex Phellodendri, 100 grams of rhubarb, 60 grams of Radix Isatidis, and 90 grams of licorice, add water 10 times the total weight of 5 traditional Chinese medicines, decoct three times, the first time for 2 hours, and the next two times each for 1.5 h, combining three decoctions, filtering, and concentrating the filtrate to obtain extract A of five kinds of traditional Chinese medic...

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Abstract

The invention discloses an aerosol for preventing and controlling pullorum disease and a preparation method thereof. The aerosol is prepared from the following raw materials by weight / volume: 50 to 200 grams of golden thread, 50 to 200 grams of amur corktree bark, 50 to 100 grams of rhubarb, 50 to 200 grams of baical skullcap root, 50 to 200 grams of indigowoad root, 50 to 100 grams of liquoric root, 10 to 80 grams of propellant, 50 to 150 milliliters of propylene glycol, 100 to 350 milliliters of ethanol and the balance of water. The preparation method comprises the following steps of: extracting active ingredients of the golden thread, the amur corktree bark, the rhubarb, the indigowoad root and the liquoric root and extracting active ingredients of the baical skullcap root; and mixing the extracts, adjusting pH value, filtering, adding active carbon to adsorb impurities, leaching, adding the propylene glycol, the ethanol and the water, adjusting the pH value to an acid state, adding the water until the volume is 1,000 milliliters, mixing uniformly, packaging and filling after a product is up to the standard and introducing the propellant after covering so as to obtain the aerosol. The product has the effects of clearing away heat, reducing fire, diminishing inflammation and relieving dysentery and has the advantages of convenient administration, safety, nontoxicity, no medicament residue, difficult medicament tolerance and high efficiency.

Description

technical field [0001] The invention specifically relates to an aerosol for preventing and treating pullorum in chicks, and also relates to a preparation method of the aerosol. Background technique [0002] Chicken pullorum is an acute, septic infectious disease caused by Salmonella, which occurs all over the world, with high morbidity and mortality. The incidence and mortality of chicken pullorum within 2 to 3 weeks Highest. The sick chickens are mainly characterized by white loose stools and sticky anus of young chickens, showing loss of appetite, head shivering, lethargy, diarrhea, and necrotic nodules on the myocardium, liver, lungs and other organs. Pathological autopsy: malabsorption of yolk, shrunken yolk sac, and pale yellow, greasy, and cheese-like contents can be seen; some chickens can be seen with suppurative arthritis, liver enlargement, hemorrhage, earthy yellow, and large gray-white necrotic foci of milia , gallbladder expansion, spleen enlargement, bleeding...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/12A61P31/04A61P1/12
CPCY02A50/30
Inventor 吴红云李建正李凤娟
Owner ZHENGZHOU HOUYI PHARMA
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