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Chinese medicinal herbal compound preparation for killing ichthyophthirius multifiliis and preparation method and application

The technology of compound preparation and Chinese herbal medicine is applied in the directions of pharmaceutical formulas, medical preparations containing active ingredients, anti-infective drugs, etc. It can solve the problems of fish death, high residue, polluted water environment, etc. Broad application prospects, easy decomposition effect

Inactive Publication Date: 2010-12-29
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The parasite causes the respiratory function and surface excretion dysfunction of the diseased fish, thus causing the death of the infected fish and causing serious economic losses
Malachite green or mercurous nitrate and mercurous acetate are mainly used in domestic and foreign aquatic industry to treat melon worm disease. These drugs are highly toxic and strong carcinogenic and teratogenic agents. Prohibited by the governments of various countries for use in aquatic products
At present, there is a lack of safe and effective drugs for the treatment of small melon worm disease in aquatic products.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 200 grams of papaya fruit, 100 grams of betel nut seeds, 50 grams of polygala root, 50 grams of cinnamon bark, 50 grams of pokeweed root, and 50 grams of eucalyptus leaves, with a total weight of 500 grams.

[0026] The papaya fruit of this embodiment is produced in Hainan, the betel nut seeds are produced in Hainan, the polygala root is produced in Sichuan, the cinnamon bark is produced in Guangdong, the pokeweed root is produced in Sichuan, and the eucalyptus leaves are produced in Sichuan or Guangdong.

[0027] The above-mentioned raw materials were dried in an oven at 60°C to constant weight, crushed and passed through an 80-mesh sieve to obtain dry powders of the raw materials, which were sealed in plastic bags and stored in a dry environment for later use. Mix the dry powders of the above-mentioned raw materials and soak them in 15L of tap water heated to 50°C for 1 hour, then decoct them, and decoct them with a slow fire for 1 hour at the first time. Once for 45 ...

Embodiment 2

[0041] 150 grams of papaya fruit, 170 grams of betel nut seeds, 50 grams of polygala root, 50 grams of cinnamon bark, 50 grams of pokeweed root, 30 grams of eucalyptus leaves, with a total weight of 500 grams.

[0042] The source of each crude drug in this embodiment is the same as that in Example 1.

[0043] The above raw materials were dried in an oven at 55°C to constant weight, crushed and sieved through an 80-mesh sieve to obtain dry powders of the raw materials, which were sealed in plastic bags and stored in a dry environment for later use. Mix the dry powders of the above-mentioned raw materials and soak them in 7.5L of water heated to 60°C for 50 minutes, then decoct them with a slow fire for 1 hour. Boil once for 45 minutes, filter with three layers of gauze, then filter with silk sieve, combine the filtrate twice, then boil and concentrate, so that the drug concentration is equivalent to 100 grams of the original drug / liter, and the Chinese herbal medicine compound ...

Embodiment 3

[0057] 170 grams of papaya fruit, 120 grams of betel nut seeds, 65 grams of polygala root, 55 grams of cinnamon bark, 60 grams of pokeweed root, 30 grams of eucalyptus leaves, with a total weight of 500 grams.

[0058] The source of each crude drug in this embodiment is the same as that in Example 1.

[0059] The above-mentioned raw materials were dried in an oven at 65°C to constant weight, crushed and passed through a 60-mesh sieve to obtain dry powders of the raw materials, which were sealed in plastic bags and stored in a dry environment for later use. Mix the dry powders of the above-mentioned raw materials and soak them in 15L of tap water heated to 55°C for 1 hour, then decoct them, and decoct them with a slow fire for 1 hour at the first time. One time for 45 minutes, after filtering with three layers of gauze, and then filtering with a sieve, the filtrates were combined twice, then boiled and concentrated, so that the drug concentration was equivalent to 100 grams of ...

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Abstract

The invention provides a Chinese medicinal herbal compound preparation for killing ichthyophthirius multifiliis and a preparation method and application thereof. The Chinese medicinal herbal compound preparation consists of the following raw material medicaments in percentage by weight: 30 to 40 percent of papaya, 20 to 34 percent of areca seed, 10 to 14 percent of thinleaf milkwort root-bark, 10 to 13 percent of cassia bark, 10 to 12 percent of pokeberry root and 6 to 10 percent of eucalyptus leaf. The preparation method of the Chinese medicinal herbal compound preparation comprises the following steps of: drying and crushing each raw material medicament respectively, and sieving to obtain dry powder of each raw material medicament; mixing the dry powder of each raw material medicament, adding water for soaking, decocting for two times, filtering, and combining two-time filtrate to obtain filtrate a; and boiling the filtrate a for concentrating to make each liter of filtrate contain 100g of raw material medicaments so as to obtain the Chinese medicinal herbal compound preparation. The Chinese medicinal herbal compound preparation is safe, effective and environmental-friendly and can be used for preventing and treating ichthyophthiriasis of fishes.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a compound Chinese herbal medicine preparation for killing fish parasitic melon worms with many eggs, and a preparation method and application thereof. Background technique [0002] Ichthyophthirius multifiliis is widely parasitic in the gills and skin of various freshwater fish, causing tissue hyperplasia and forming white spots, which is called white spot disease. The parasite causes the respiratory function and body surface excretion dysfunction of the diseased fish, thus causing the death of the infected fish and causing serious economic losses. Malachite green or mercurous nitrate and mercurous acetate are mainly used in domestic and foreign aquatic industry to treat melon worm disease. These drugs are highly toxic and strong carcinogenic and teratogenic agents. It is banned from use in aquatic products by governments of various countries. At presen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61P33/02A61P33/14
Inventor 张其中鉏超
Owner JINAN UNIVERSITY
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