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Blood purification base displacing liquid

A technology of blood purification and replacement fluid, which is applied in the direction of blood diseases, extracellular fluid diseases, active ingredients of alkali/alkaline earth metal chlorides, etc., to reduce the risk of configuration contamination, stabilize the internal environment of the body, and simplify the configuration of replacement fluid.

Inactive Publication Date: 2010-12-15
宋青 +3
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a blood purification basic replacement solution that can meet the continuous blood purification treatment needs of critically ill patients, which not only overcomes the need for ready-to-use at the bedside Disadvantages such as pollution and cumbersome configuration process brought by the replacement fluid are also convenient for the rapid configuration of bicarbonate in clinical practice, without causing complications such as lactic acidosis and hyperglycemia, and stabilizing the internal environment of the body to the greatest extent

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0012] Take NaCl 27g, MgSO 4 0.8g and CaCl 2 1g, dissolved in an appropriate amount of water for injection, according to the conventional preparation method of large infusion, after stirring, initial filtration, adding water for injection to a total volume of 4000ml, after terminal filtration, filled in medical plastic infusion bags, sealed and sterilized.

[0013] Example 2 (hypotonic base replacement fluid)

Embodiment 2

[0014] Take NaCl 24.3g, MgSO 4 0.88g and CaCl 2 1.1g, dissolved in an appropriate amount of water for injection, according to the conventional preparation method of large infusion, after stirring, initial filtration, adding water for injection to a total volume of 4000ml, after terminal filtration, filled in medical plastic infusion bags, sealed, and sterilized.

[0015] Example 3 (hypertonic base replacement fluid)

Embodiment 3

[0016] Take NaCl 29.7g, MgSO 4 0.72g and CaCl 2 0.9g, dissolved in an appropriate amount of water for injection, according to the conventional preparation method of large infusion, after stirring, initial filtration, adding water for injection to a total volume of 4000ml, after terminal filtration, filled in medical plastic infusion bags, sealed, and sterilized.

[0017] Example 4 (half sugar base replacement solution)

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PUM

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Abstract

The invention discloses blood purification base displacing liquid. Each hundred milliliter of water for injection contains 607.5 to 742.5 milligrams of NaCl, 18 to 22 milligrams of MgSO4 and 22.5 to 27.5 milligrams of CaCl2 which form sugar-free base displacing liquid. Based on a formula of the sugar-free base displacing liquid, 625 to 1,250 milligrams of glucose is added to form sugar-containing base displacing liquid. The blood purification base displacing liquid can meet the requirement of serious patients for continuous blood purification treatment, overcomes the defects of pollution and fussy preparation process caused by preparing the ready-to-use displacing liquid beside a bed, facilitates quick preparation of clinical bicarbonate, realizes personalized treatment, and can effectively avoid complications such as hyperkalemia, lactic acidosis, hyperglycemia and the like and furthest stabilize the internal environment of the patient body.

Description

technical field [0001] The invention belongs to the technical field of medicine manufacturing and relates to a basic replacement fluid, in particular to a blood purification basic replacement fluid suitable for metabolic disorders in the body. Background technique [0002] For critically ill patients, especially patients with multiple organ dysfunction syndrome (MODS) in the intensive care unit (ICU), continuous blood purification (CBP) has been used in recent years , CBP) technology, which removes the damage factors involved in the occurrence and development of MODS in the blood, down-regulates the inflammatory response, and improves the prognosis of MODS, has gradually become one of the effective methods for the treatment of MODS. [0003] In the continuous blood purification technology, on the one hand, the replacement fluid acts as a carrier for removing substances to remove metabolites and poisons in the body, and on the other hand, it can supplement the substances lac...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/14A61P7/08A61K33/06
Inventor 周飞虎宋青唐晟董黎
Owner 宋青
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