Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Gel for teeth tissues remineralization

A remineralization, gel technology, applied in dentistry, digestive system, drug combination, etc., can solve problems such as difficult to use at home

Inactive Publication Date: 2010-12-08
WDS
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The necessity of a film set and the duration of dissolution make it difficult for patients to use the formulation at home

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Gel for teeth tissues remineralization
  • Gel for teeth tissues remineralization

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Patient X, 38 years old, complained of hypersensitivity and unsatisfactory cosmetic tooth appearance.

[0046] During the first inspection on April 4, 2005, it was determined that:

[0047] HI (Health Index) *) -1.95 points

[0048] ITHP *) -54%

[0049] ITHI *) -2.8 points

[0050] *) -Yu.A.Fedorov, V.A.Drozhzhina, Clinical course, diagnostics and treatment of noncarious lesions of teeth. Novoe v stomatologii, No.10(60), 1997, special issue.).

[0051] Tooth color according to the Vita scale - C3, insufficient gloss

[0052] Patients were given a four-week course of formulation application using barrier swabs.

[0053] The next inspection was 4 weeks later on May 3, 2005. No complaints.

[0054] Objective data:

[0055] HI (hygienic index) -1.57 points

[0056] ITHP - 6.2%

[0057] ITHI-0

[0058] According to Vita scale tooth color - C1, the luster becomes more intense.

Embodiment 2

[0060] Patient Y, 28 years old, on June 9, 2005 complained of tooth hypersensitivity, partial lack of luster and unsatisfactory tooth color.

[0061] Objective data:

[0062] HI-2.17 points

[0063] ITHP - 62.5%

[0064] ITHI-2.1 points

[0065] Tooth color could not be determined, but it was noted that yellow tones predominated over white tones.

[0066] Daily application of the formulation for 3 weeks using a standard dental tray is recommended.

[0067] The next inspection was three weeks later on July 8, 2005. There were no complaints, and the patient noted negligible reactions when eating very cold food (ice cream).

[0068] objective data

[0069] HI (hygienic index) -1.5 points

[0070] ITHP - 9.3%

[0071] ITHI-1.1 points

[0072] The whitening of the teeth is visually noted and the tooth shine becomes more intense, which satisfies the patient.

Embodiment 3

[0074] Patient Z, 36 years old, complained of tooth hypersensitivity following a home bleaching procedure. During the first inspection on August 2, 2005, it was determined that:

[0075] Tooth color according to the Vita scale - C2, lack of luster

[0076] HI-1.9 points

[0077] ITHI-2.1 points

[0078] ITHP - 62.5%

[0079] Daily application of the formulation for 4 weeks using a standard dental tray is recommended. The next inspection was 4 weeks later on August 31, 2005. No complaints.

[0080] Tooth color according to the Vita scale - A1, the tooth luster becomes more intense.

[0081] ITHP, ITHI-0

[0082] HI-1.2 points

[0083] The results assembled following observations on the effect of remineralizing gels have been correlated with data obtained in experiments with fluoride toothpastes and gels that are more frequently used for these purposes in today's practice.

[0084] Main Group (Remineralization Gel)

[0085] Association group (fluoride toothpaste and ge...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

Technical result of the invention is achieved by practical use of effective remineralizing formulation containing accessible components, which can be used by a patient without any help for caries prophylaxis, non-carious affections treatment, teeth hypersensitivity treatment and teeth visual appearance (color and gloss) improvement. The problem specified is solvable by preparing gel comprising xylitol 2-25 wt. %, calcium glycerophosphate 0.1-3.0 wt. %, magnesium ion source 0.01-0.50 wt. % and guar gum 0.03-0.30 wt. % as active components and inert components as well used for teeth gels preparation, herein as magnesium ion source there is used magnesium chloride, magnesium sulfate or magnesium nitrate.

Description

[0001] Application field [0002] The present invention relates to stomatology and fragrance industry, in particular to gels for remineralization of dental tissue. Background of the invention [0003] A formulation containing calcium gluconate, cellulose gum, dimethylsulfoxide, nitrofurazone, glycerol and water designed for remineralization of tooth tissue is known (SUA3 No. 1774870, IPC 5 A61K 6 / 02, 1992). [0004] The prepared formulation is dried and then used in the form of an elastic film for the coating of the damaged part of the tooth, the surface of which has been previously cleaned to remove dental deposits. The applied film is wetted by saliva, transforms into a gel, and gradually disintegrates for 60-120 minutes, thereby providing a prolonged release of the remineralizing substance and its spreading effect on the solid tooth tissue. The necessity of a film set and the duration of dissolution make it difficult for patients to use the formulation at home. Contents ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/60A61K8/19A61Q11/00
CPCA61K8/731A61K8/19A61K8/55A61Q11/00A61K8/737A61K8/042A61K8/345A61P1/02
Inventor T·O·曼纳斯赫诺夫S·K·马特洛塔吉娅娜·弗拉基米洛夫娜·库贝
Owner WDS
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com