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Compound doxycycline hydrochloride injection for treating intestinal diseases of animals and preparation method thereof

A technology for doxycycline hydrochloride and intestinal diseases, which is applied in the direction of active ingredients of tetracycline, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., and can solve unsatisfactory curative effects, untimely treatment, breeding To avoid problems such as industry losses, and to achieve the effects of expanding the breadth of intestinal antibacterial spectrum, accurate dosage, and advanced production technology

Inactive Publication Date: 2010-09-08
胡少平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Intestinal disease of livestock and poultry is a common disease, if it is not treated in time, it will seriously affect its growth and cause great losses to the breeding industry
At present, there are many products on the market for intestinal diseases of livestock and poultry, but most of them are unsatisfactory in curative effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] A doxycycline hydrochloride compound injection is prepared from 10 parts by weight of raw materials doxycycline hydrochloride, 25 parts by weight of sulfamethoxazole, 1 part by weight of sodium bisulfite, 0.1 parts by weight of disodium edetate, and 950 parts by weight of propylene glycol.

[0024] The preparation method is as follows: respectively weigh the main drug in the prescribed amount, add an appropriate amount of solvent for injection, stir and dissolve, then add the prescribed amount of antioxidant and disodium ethylenediamine tetraacetate, stir and dissolve, and add the remaining amount of solvent for injection To the full amount, that is.

Embodiment 2

[0026] A doxycycline hydrochloride compound injection, which is composed of 50 parts by weight of raw materials doxycycline hydrochloride, 125 parts of sulfamethoxazole, 1 part of sodium formaldehyde sulfoxylate, 0.2 parts of disodium edetate, and 900 parts of glycerin formal formulated.

[0027] Its preparation method is identical with embodiment 1.

Embodiment 3

[0029] A doxycycline hydrochloride compound injection, prepared by weight parts of raw materials doxycycline hydrochloride 100, sulfamethoxazole 250, sodium thiosulfate 2, edetate disodium 0.1, dimethylformamide 700 made.

[0030] Its preparation method is identical with embodiment 1.

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PUM

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Abstract

The invention discloses compound doxycycline hydrochloride injection for treating intestinal diseases of animals, and the injection comprises principle agent, addition agent and solvent, wherein the principle agent is prepared by the following raw materials in parts by weight: 10-100 parts of doxycycline hydrochloride and 25-250 parts of sulfamethoxazole, or 10-100 parts of mequindox, or 10-100 parts of colistin sulfate, the addition agent is prepared by the following materials in parts by weight: 1-2 parts of antioxidant and 0.1-0.2 part of ethylene diamine tetraacetic acid-2Na, and the solvent is prepared by 650-980 parts of solvent for injection by weight. Clinical tests prove that the compound doxycycline hydrochloride injection for treating intestinal diseases of animals has better treating effects than unilateral preparations which respectively include each medicine and has the characteristics of wide antimicrobial spectrum, strong antibacterial activity, safe use and approval treating effects.

Description

technical field [0001] The invention relates to a veterinary doxycycline hydrochloride compound injection for treating intestinal diseases and a preparation method thereof. Background technique [0002] Intestinal diseases of livestock and poultry are common occurrences, and if they are not treated in time, their growth will be seriously affected, causing great losses to the breeding industry. Currently, there are many products on the market for intestinal diseases of livestock and poultry, but most of them have unsatisfactory curative effects. Contents of the invention [0003] The object of the present invention is to provide a veterinary doxycycline hydrochloride compound injection for treating intestinal diseases with safe use, definite curative effect and wide antibacterial spectrum and its preparation method. [0004] The veterinary doxycycline hydrochloride compound injection for treating intestinal diseases of the present invention comprises a main drug, an additi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/12A61K31/65A61K9/08A61K47/18A61P31/04A61P1/00A61K31/635A61K31/498
CPCY02A40/70
Inventor 胡少平
Owner 胡少平
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