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Chinese medical herbs aerosols for treating anchylosis, painful swelling and preparation method thereof

A technology for joint stiffness and spray, which is used in pharmaceutical formulations, aerosol delivery, non-central analgesics and other directions, can solve problems such as the inability to promote joint function recovery, achieve analgesic joint stiffness and movement disorders, and improve joint stiffness. and activity disorders, clinical symptoms improvement effect

Inactive Publication Date: 2011-09-07
河南省正骨研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the adverse reactions of chemical drugs and the defects of simple anti-inflammatory and pain relief that cannot promote the recovery of joint function, its use is limited.
Traditional Chinese medicine has definite effects in anti-inflammation, detumescence, pain relief and promotion of joint function recovery, but in-depth research is still needed on the rationality, feasibility, effectiveness and ease of use of prescription, dosage form, technology and curative effect

Method used

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  • Chinese medical herbs aerosols for treating anchylosis, painful swelling and preparation method thereof
  • Chinese medical herbs aerosols for treating anchylosis, painful swelling and preparation method thereof
  • Chinese medical herbs aerosols for treating anchylosis, painful swelling and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Composition and consumption of the pharmaceutical raw material that constitute spray of the present invention, by weight percentage:

[0067] Clematis 16, Guizhi 12, Danshen 12, Shenjincao 12, Angelica 12, Duhuo 12, Frankincense 6, Myrrh 6, Dried Ginger 6, Safflower 6

[0068] Its adjuvant and its addition amount, according to its percentage of the total volume of the pharmaceutical solution: Tween-801.5%.

[0069] The preparation method of described spray:

[0070] 1. Crush clematis, cinnamon twig, salvia miltiorrhiza, shenjincao, angelica, lovage, frankincense, myrrh, dried ginger, and safflower into coarse powder, soak in 6 times the amount of 95% ethanol solution for 2 hours, and extract by hot reflux 2 hours, filter. Add 4 times the amount of 95% ethanol solution to the dregs, extract under reflux for 1 hour, and filter. Add 4 times the amount of 95% ethanol solution to the dregs, extract under reflux for 1 hour, and filter. The filtered extracts were combined,...

Embodiment 2

[0074] Composition and consumption of the medicinal raw materials constituting the spray of the present invention, by weight percentage: Clematis 15, Guizhi 15, Salvia miltiorrhiza 15, Shenjincao 15, Angelica 10, Duhuo 10, Frankincense 5, Myrrha 5, dried Ginger 5, safflower 5

[0075] Its adjuvant and its addition amount, according to its percentage of the total volume of the pharmaceutical solution: Tween-801%.

[0076] The preparation method of the spray preparation method:

[0077] 1. Crush clematis, cinnamon twig, salvia miltiorrhiza, shenjincao, angelica, lovage, frankincense, myrrh, dried ginger, and safflower into coarse powder, soak in 6 times the amount of 80% ethanol solution for 2 hours, and extract by hot reflux 2 hours, filter. Add 4 times the amount of 80% ethanol solution to the dregs, extract under reflux for 1 hour, and filter. Add 4 times the amount of 80% ethanol solution to the dregs, extract under reflux for 1 hour, and filter. The filtered extracts we...

Embodiment 3

[0081] Composition and consumption of the pharmaceutical raw material that constitute spray of the present invention, by weight percentage:

[0082] Clematis 14, Guizhi 18, Danshen 18, Shenjincao 18, Angelica 8, Duhuo 8, Frankincense 4, Myrrh 4, Dried Ginger 4, Safflower 4

[0083] Its adjuvant addition (according to its total volume %) of the pharmaceutical solution: Tween-800.5%.

[0084] The preparation method of described spray:

[0085] 1. Crush clematis, cinnamon twig, salvia miltiorrhiza, shenjincao, angelica, lovage, frankincense, myrrh, dried ginger, and safflower into coarse powder, soak in 6 times the amount of 70% ethanol solution for 2 hours, and extract by hot reflux 2 hours, filter. Add 4 times the amount of 70% ethanol solution to the dregs, extract under reflux for 1 hour, and filter. Add 4 times the amount of 70% ethanol solution to the dregs, extract under reflux for 1 hour, and filter. The filtered extracts were combined, ethanol was recovered under red...

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Abstract

The invention discloses Chinese medical herbs aerosols for treating anchylosis, painful swelling and a preparation method thereof. The Chinese medical herbs aerosols comprises the following components according to the percentage by weight: 10-20 of clematis chinensis, 10-20 of cassia twig, 10-20 of salvia miltiorrhiza, 10-20 of lycopodium calvatum, 5-15 of angelica, 5-15 of heracleum hemsleyanum michaux, 2-10 of frankincense, 2-10 of myrrh, 2-10 of rhizoma zingiberis, and 2-10 of safflower; the component and usage of accessories is 05-2 of Tween-80 according to the percentage thereof of the total volume of the liquid medicine. The preparation method thereof is as follows: medicinal materials are ground and extracted by 70%-95% of ethanol solution hot reflux, the extracting solution is decompressed and concentrated into dense paste, medicinal material residue is added with water for hot extracting, the extracting solution is concentrated into a defined volume and added with the Tween-80, stirred, dissolved, and added into the dense paste and filtered. The pharmacodynamics experiment proves that the medicine has obvious functions of anti-inflammatory, detumescence, relieving pain and promoting the recovery of the function of joint.

Description

technical field [0001] The invention relates to a medicine for external use and its preparation, and mainly provides a traditional Chinese medicine spray for treating joint stiffness and swelling and pain and a preparation method thereof. Background technique [0002] In daily life, due to local joint damage, inflammation, chronic strain, long-term immobilization, physiological degeneration and other reasons, it is easy to cause joint stiffness, swelling and pain symptoms, resulting in limited joint function and seriously affecting people's normal activities. The current treatment usually adopts chemical medicines with anti-inflammatory and analgesic effects for internal or external use or traditional Chinese medicines with blood circulation promoting and blood stasis dispelling, swelling and pain relieving, and meridians relaxing. The defects that chemical drugs cannot promote the recovery of joint function due to the existence of adverse reactions and simple anti-inflammat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61K9/12A61P19/02A61P29/00
Inventor 陈宝龙王健智凌春莹冯坤
Owner 河南省正骨研究院
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