Method for preparing total polyphenol of Loropetalum chinense (R. Br.) Oliver for treating burn and scald

Abstract

The invention discloses a method for preparing loropetalum chinense total polyphenol for treating burn and scald, and relates to a drug for treating the burn and scald. The invention provides the method for preparing the loropetalum chinense total polyphenol for treating the burn and scald, which comprises that: Loropetalum chinense leaves are pulverized, are added with acetone, are soaked, and are filtered to obtain filtrate and filter residue; the filter residue is added with the acetone, is soaked, is extracted for at least one time, and is filtered; the filtrate is combined and is condensed to obtain an upper column solution; the acetone is reclaimed; the upper column solution is added to a macroporous resin column and is eluted with water or ethanol till an eluant is close to colorless; the eluant is collected; and the ethanol is reclaimed is condensed, and is dried to obtain the loropetalum chinense total polyphenol. The preparation method is simple and suitable for industrialized production; and in-vivo / in-vitro tests prove that the prepared loropetalum chinense total polyphenol extract with mass percentage of total polyphenol of more than or equal to 50 percent has good functions of resisting inflammation, relieving heat, easing pain, resisting bacteria, and the like, and can be applied to the preparation of a drug for treating burn, sunburn and trauma. The loropetalumchinense total polyphenol can be prepared into soft plaster, gel, troche, capsule, soft capsule, oral liquid, syrup, drop pill, injection, and other preparations.

Description

A preparation method of loropetalum polyphenols for treating burns and scalds technical field The invention relates to a medicine for treating burns and scalds, in particular to a preparation method of total polyphenols of loropetalum for treating burns, sunburns and traumas. Background technique Burn, sunburn, trauma are a kind of commonly encountered diseases, often take place in daily life, and the burn incidence rate such as fire, gas explosion burn and water, oil scald is very high, is about 2%. Sunburn is a disease that is often overlooked but seriously affects human health. In mild cases, it can cause redness, swelling, and peeling, and in severe cases, it can cause skin cancer, especially for workers, farmers, and soldiers who work outdoors for a long time. Ultraviolet burns and sunburns The incidence rate is higher. With the deterioration of the environment, the greenhouse effect, the intensity of ultraviolet rays is getting higher and higher, and sunburn has att...

AI Technical Summary

Problems solved by technology

In China, the main drug dosage forms of conservative therapy are patches and ointments, etc. In addition to Yunnan Baiyao and scalding ointment, there is still a lack of a drug with definite curative effect, short course of treatment, high cure rate, small adverse reactions, and economical convenience in the market

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