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Use of pu'er tea in preparing medicament for treating or preventing diabetes

A technology for Pu'er tea and diabetes, applied in the field of Pu'er tea, can solve the problems of insufficient depth and extensive Pu'er tea, and achieve the effects of simple preparation method, abundant sources, and no toxic and side effects.

Inactive Publication Date: 2009-04-22
普洱市人民政府茶产业发展办公室科技服务中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the research on Pu'er tea has been relatively extensive and not deep enough; the efficacy of Pu'er tea still needs to be further developed.

Method used

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  • Use of pu'er tea in preparing medicament for treating or preventing diabetes
  • Use of pu'er tea in preparing medicament for treating or preventing diabetes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] ——Preparation example of Pu'er tea powder

[0037] Dried Pu-erh tea: water = 1:10-20 (W / V), boil at 100°C for 10-30 minutes, filter through a 120-mesh sieve to remove residue, and collect the water extract. Repeat this step 2 to 4 times, and combine the extracts each time. The total extract was filtered through a 200-mesh sieve and a 0.45 μM filter, and then spray-dried at high temperature to obtain Pu'er tea powder.

Embodiment 2

[0039]——Using the Pu’er tea powder prepared in Example 1 to study its hypoglycemic effect on type II diabetes model mice: the experimental animals used in this experiment: all type II diabetes model mice——db / db (Leptin receptor knockout Type 2) mice (purchased from the National Genetic Mouse Resource Bank of Nanjing University), half male and half male, were divided into 3 groups, namely the type II diabetes model group (positive), the type II diabetes model positive drug (metformin) group, Give Pu'er tea (powder) group. Every group of db / db mice only n=9, administration method: the positive medicine (metformin) group is gavage, 200mg / kg, administration 1 time every day; Pu'er tea group and model group only give Pu'er tea (powdered ) water and tap water, no amount, the mice freely ingested, wherein the Pu'er tea water was prepared with the Pu'er tea powder prepared in Example 1, and the concentration was 0.5% (W / V). Table 1 shows the changes in the blood glucose values ​​of e...

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Abstract

The invention discloses Puerh tea and application of a preparation thereof to preparation of a medicine for treating or preventing diabetes. A product can inhibit the activity of protein tyrosine phosphatase 1B, and can be taken as a constituent of food, medicines or medicine compositions for diseases related to the protein tyrosine phosphatase 1B; and the product can be taken as food, a medicine or a medicine composition for treating a series of diseases related to the PTP1B such as diabetes, obesity and so on. The invention provides the Puerh tea and the novel application of the preparation thereof, and discloses good pharmaceutical prospect.

Description

technical field [0001] The present invention relates to the application of Pu'er tea, more specifically, relates to the application of Pu'er tea and its preparation in the preparation of medicine for treating or preventing diabetes. Background technique [0002] As we all know, diabetes is a common disease that seriously endangers human health. Diabetes will not heal for life, and its complications are extensive and serious. It is worthy of vigilance that in recent years, diabetes has a tendency to increase year by year, and the age of onset is getting younger. How to find a safe and effective drug for treating diabetes has been a technical problem that people have long been eager to solve but have not been successful. [0003] Diabetes is clinically divided into two types: type I diabetes and type II diabetes, of which type II diabetes accounts for 80% to 90% of the total number of cases, and more than 100 million people in the world suffer from type II diabetes. The etiol...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61P3/02A61P3/04
Inventor 盛军付学奇沈培平李婷王亚军陈颖丽郝淑美赵昌能杨柳霞季爱兵李艳华
Owner 普洱市人民政府茶产业发展办公室科技服务中心
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