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Free radical network scavenger

A free radical and scavenger technology, which is applied in skin care preparations, cosmetics, cosmetic preparations, etc., can solve the problems of not being prepared, and achieve the effect of delaying skin aging, rejuvenation and vitality

Inactive Publication Date: 2009-02-04
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, if a kind of free radical (hydroxyl free radical) with the strongest attack power and free radical (R , RO 2 ) free radical network scavenger can effectively prevent skin aging caused by free radical damage, but there is no free radical network scavenger that can scavenge various free radicals

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1, the detection of the ability of Chinese herbal medicine extract to scavenge various free radicals

[0030] 1. Preparation of Chinese herbal medicine extract

[0031] The 7 kinds of Chinese herbal medicines of Forsythia, Polygonum cuspidatum, Myrobalan, Rosa laevigata, cinnamon, rhubarb and licorice were respectively pulverized with a pulverizer and passed through a 120-mesh sieve. Weigh 30g of the crushed Chinese herbal medicines and place them in a 100mL ground-mouth Erlenmeyer flask, add 300mL of absolute ethanol, shake in a full-temperature air-bath shaker (55°C, 150rpm) for 1 hour, filter with filter paper, collect the filtrate, and precipitate Then add 300 mL of absolute ethanol, repeat the above steps 2 times. After combining the three filtrates, use absolute ethanol to quantify to 900 mL as the obtained sample solution.

[0032] 2. Determination of the ability of Chinese herbal medicine extracts to scavenge total free radicals

[0033] Take 0.4mL...

Embodiment 2

[0100] Embodiment 2, the determination of the free radical network scavenger scavenging ability prepared with 6 kinds of Chinese herbal medicine extracts

[0101] Cinnamon is a Chinese herbal medicine with the same origin as medicine and food, myrobalan and Rosa chinensis are raw materials for functional food, forsythia, knotweed, and rhubarb are conventional Chinese herbal medicines, and the above-mentioned Chinese herbal medicine extracts are not listed in the national cosmetic hygienic standards. Chinese herbal medicine extract, so the safety is also higher. The raw material compound of 12 free radical network scavengers was designed by DPS software. Among the 12 free radical network scavengers, the ratio of each raw material is shown in Table 5.

[0102] The raw material composition of table 5 free radical network scavenger (weight: g)

[0103]

[0104] Weigh various Chinese herbal medicines according to the proportioning in Table 5, pulverize the various Chin...

Embodiment 3

[0109] Embodiment 3, the determination of the free radical network scavenger scavenging ability prepared with 3 kinds of Chinese herbal medicine extracts

[0110] Using forsythia, Polygonum cuspidatum and Myrobalan as raw materials, 4 raw material compounds of free radical network scavengers were designed. Among the four free radical network scavengers, the ratio of each raw material is shown in Table 7.

[0111] The raw material composition of table 7 free radical network scavenger (weight: g)

[0112]

[0113] Weigh various Chinese herbal medicines according to the proportioning in Table 7, pulverize the various Chinese herbal medicines with a pulverizer and pass through a 120-mesh sieve. Take 30 g of the pulverized Chinese herbal medicine powder mixture and place it in a ground-mouth Erlenmeyer flask, add 300 mL of absolute ethanol, vibrate in a full-temperature air-bath shaker (55 ° C, 150 rpm) for 1 hour, filter with filter paper, collect the filtrate, and pre...

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Abstract

The invention discloses a free radical network scavenging agent. The free radical network scavenging agent of the invention is obtained by extracting raw materials which comprise forsythia, giant knotweed and myrobalam by organic solvent. The parts by weight of the forsythia, the giant knotweed and the myrobalam in the raw materials are respectively 4-31 parts, 12-29 parts and 1-51 parts; the organic solvent is absolute ethyl alcohol. The free radical network scavenging agent of the invention can play tremendous role in the production of functional cosmetics such as anti-aging, whitening, sunscreen, after-sun repair, etc.

Description

technical field [0001] The invention relates to a free radical network scavenger, in particular to screening the free radical network scavenger from Chinese herbal medicines. Background technique [0002] Today, as people's living standards are improving day by day, effective skin care has become an important part of improving the quality of life. Among them, cosmetics such as anti-aging, freckle removal, and sunscreen are increasingly popular. Therefore, screening additives with the above effects has become a research topic at home and abroad. focus. At present, there are dozens of mechanisms to explain skin aging, such as the theory of endocrine function decline, immune function decline, cross-linking theory, free radical damage theory, etc., among which the free radical damage theory has received special attention (Li Suyun, Wang Liqin, Zheng Jialin, Liu Xiaoqian. Research progress on free radicals and aging. Chinese Journal of Gerontology, 2007, 27: 2046-2048). The mai...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/08A61Q19/02A61Q17/04A61Q19/00
Inventor 王友升刘祎李莉许牧遥
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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