Reduction of saltiness with sweeteners

A sweetener and saltiness technology, which is applied to the user's willingness to take a cleaning solution, selected from the isomerization field of chlorinated sucrose, and can solve problems such as intolerance

Inactive Publication Date: 2008-10-08
C B FLEET CO INC
View PDF0 Cites 1 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Often, subjects cannot tolerate taking the entire initial dose of the formulation,

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Reduction of saltiness with sweeteners
  • Reduction of saltiness with sweeteners
  • Reduction of saltiness with sweeteners

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1 : Test sucrose, saccharin, sucralose, aspartame, Ace-K, sweet protein (Talin), neohesperidin dihydrochalcone (NHDC) and trehalose in FLEET PHOSPHO-SODA in the stability. Among these sweeteners, sucralose, Ace-K and saccharin were found to have acceptable stability in laxatives. Although other sweeteners retain their effectiveness when blended, their effectiveness decreases over time.

Embodiment 2

[0037] Example 2 : Preparation of phosphate bowel cleansers for optimal comparison. Exemplary compositions were prepared as shown in the table below. Percentages are in weight / weight (w / w).

[0038] Table 1

[0039] components

Embodiment 3

[0040] Example 3 : To determine whether subjects prefer the taste of salty liquids with or without sweeteners, a pleasure-type preference trial was conducted on 40 subjects. Each subject was asked to rate the two saline liquids on a scale of 1 to 9, with 1 being highly preferred and 9 being least preferred. A 2% NaCl / water solution containing 1.29% ginger flavor was prepared.

[0041] The first NaCl / water solution (T in Table 2 below) contained no sweetener, while the second NaCl / water solution (G in Table 2 below) contained 0.13% sucralose. Similarly, unsweetened (J in Table 2 below) and sweetened (K in Table 2 below) phosphate bowel cleansers were prepared. Compared to the phosphate cleanser in Example 2, these cleanses contained 1.3% ginger flavoring instead of cola.

[0042] Table 2

[0043]

[0044] As can be seen from the data in Table 2, subjects preferred the sweet, saline liquid G by about 47% for the 2% saline solution, and about 45% for t...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The present invention provides compositions for bowel cleansing that have improved palatability through the inclusion of a sweetener, such as a chlorinated sucrose isomer. The invention also provides methods of reducing the saltiness of an orally consumed substance, including phosphate salt and PEG/salt bowel cleansers, through the use of a sweetener. Utilizing a sweetener including Sucralose to reduce the saltiness of a substance unexpectedly contradicts the conventional belief that sweeteners amplify saltiness.

Description

[0001] References to related applications [0002] This application claims the benefit of U.S. Provisional Application No. 60 / 724,917, entitled "Utilizing Sucralose to Reduce Saltiness," filed October 7, 2005, and claims Priority to US Application No. 11 / 465,741, entitled "Reduction of Saltiness with Sweeteners." Background technique [0003] Screening colonoscopy combined with polyp removal (polypectomy) has significantly reduced the incidence of colorectal cancer. Unfortunately, of the 147,500 new cases of colorectal cancer diagnosed in 2003, the American Cancer Society estimates that only 37 percent of these cases were diagnosed early enough to be treated to provide the best possible Prognostic treatment. [0004] Screening colonoscopies should be repeated more frequently in subjects with previous polypectomy because they are at increased risk of developing regenerative polyps. However, at least 20% of subjects with previous polypectomy did not return for their follow-up...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K9/08A61K47/36A61K47/02A61K33/42
Inventor 纳尔逊・阿亚拉奇迪・明尼克斯迈克尔・L・卡斯韦尔
Owner C B FLEET CO INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap