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Equipment for preparing pill using cold wind and trap cooling gas

A technology of cooling gas and dropping pills, applied in lighting and heating equipment, coolers, household refrigeration devices, etc., can solve the problems that the equipment cannot be completely cleaned, cannot solve the problems of organic residues, coolant residues, etc., and achieves no cleaning dead corners, No organic solvent residue, good for stability

Active Publication Date: 2011-06-08
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

Dropping pills made by cooling with oil-soluble solvents, cooling liquid residue is an unavoidable problem
Subsequent oil throwing and oil wiping processes are indispensable, but they cannot solve the problem of organic residues; at the same time, due to the adhesiveness of silicone oil and other cooling fluids, the equipment cannot be completely cleaned, which becomes a hidden danger of cross-contamination, which is a problem faced by GMP companies today

Method used

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  • Equipment for preparing pill using cold wind and trap cooling gas
  • Equipment for preparing pill using cold wind and trap cooling gas
  • Equipment for preparing pill using cold wind and trap cooling gas

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Embodiment Construction

[0032] The equipment for preparing dropping pills using cold air plus cold trap cooling gas of the present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0033] The present invention uses low-temperature air as the cooling medium, usually at a temperature lower than 0 degrees, to contact with the molten dripping pill auxiliary material, and cool it down below the freezing point to ensure the pellet forming. Usually, the dropping pills fall freely according to the gravity. The present invention uses a cold trap combined with cold air to complete heat energy exchange with the falling dropping pills in the cooling pipe to ensure the formation of the dropping pills. The cooling air is clean and filtered, which fully meets the requirements of the pharmaceutical cleanliness standard, and there is no need to worry about the contamination of the pharmaceutical. At the same time, the pipeline is easier to clean, and there is ...

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Abstract

The invention discloses a device for preparing dripping pills, which adopts cold-air plus cold trap cooling gas The device is provided with a dripping pill machine, a cooling pipeline sealed and communicated with the dripping pill machine and an air cooling device which is communicated with the cooling pipeline and feeds cold air into the cooling pipeline circularly. The dripping pill machine is provided with a material melting pot communicated with a pipeline of material liquor feeding device, a dripper communicated with the material melting pot and an insulating cavity arranged outside the dripper to carry out heat preservation on the dripper. The dripper is a hopper-shaped structure the upper and lower parts of which are communicated and the dripper is provided with 1 to 4 layers with the same shape from the outside to the inside. 1 to 4 material pots are also provided. A cut is formed at a lower opening of the insulating cavity corresponding to the dripper and is sealed and connected with an upper port of the cooling pipeline. The invention simplifies the operation working procedures, has no remnant organic solvent and reduces the cost for preparing dripping pills. The device has no dead angles when cleaning and is convenient for washing, thus avoiding cross contamination during the manufacture process and being beneficial to the product stabilization..

Description

technical field [0001] The invention relates to a pharmaceutical device. In particular, it relates to a device for preparing dropping pills with simple preparation process, no organic residue problem, no hidden danger of cross-contamination, and easy cleaning, which adopts cold air and cold trap cooling gas to prepare dropping pills. Background technique [0002] The preparation of traditional dripping pills is obtained by dropping the melted material into a liquid lysozyme immiscible with the material. The cooled lysozyme can be a water-soluble solvent or an oil-soluble solvent. Among them, water-soluble solvents are mostly water, glycerin, etc.; oil-soluble solvents are mostly paraffin oil and silicone oil. Adopt oil-soluble solvent to cool the dripping pill that makes, and the problem that cooling liquid remains is unavoidable. Subsequent oil throwing and oil wiping processes are indispensable, but they cannot solve the problem of organic residues. At the same time, due...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61J3/06F25D13/00F25D15/00
Inventor 闫希军孙小兵张文生荣昌盛王世庆章顺楠刘军
Owner TIANJIN TASLY PHARMA CO LTD
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