Portable fast joint inspection device for foetus teratogenic disease

Abstract

The invention discloses a portable rapid combined detection device of fetal teratogenic diseases, including a sample suction head (1) and a detection tube (2) which is connected at the back end of the sample suction head (1). The front end of the sample suction head (1) is provided with a thin tube suction mouth (12), the suction mouth (12) is provided with a sample suction port (13) for sample suction, the front end of the suction mouth (12) can be sheathed with a rubber protecting cap (14), an inner cavity (17) of the sample suction head can be respectively filled with sample filter materials (3) and sample water absorbent materials (4) from the front to the back, the interior of the detection tube (2) is provided with a test paper fixed column (5), a cytomegalovirus (HCMV) detection test paper strip, a herpes simplex virus (HSV) detection test paper strip, a rubella virus (RV) detection test paper strip and a toxoplasma (TOX) detection test paper strip are fixedly arranged on the test paper fixed column (5), and the tail end of the detection tube is provided with a sealing cover (7) to seal the waste after detection in the detection tube (2), so as to prevent leakage. All the detection test paper strips (6) which are sealed and fixed in the device are carried out one-time sample suction and the detection with same background, the invention can carry out the combined detection of HCMV antibody, HSV antibody, RV antibody and TOX antibody in the sample at one time within a plurality of minutes by using the naked eye, a plurality of detections of the sample become more simple, safe and rapid; furthermore, the cross-interference can be avoided, the waste after detection is still sealed in the detection tube, so the invention is conductive to the avoidance of spread of pathogens and iatrogenic infection, and is more conductive to the environmentally protective treatment of the waste.

Description

technical field [0001] The invention relates to a medical device and a sample detection test paper, in particular to a portable rapid combined detection device which can be used for diagnosing multiple teratogenic diseases of the fetus at the same time. technical background [0002] Cytomegalovirus (HCMV), herpes simplex virus (HSV), rubella virus (RV), and toxoplasma gondii (TOX) are the most likely causative agents of teratogenic diseases. If a pregnant woman suffers from one of the diseases caused by the above-mentioned pathogens, it may lead to miscarriage, stillbirth, fetal malformation, etc., or long-term sequelae such as mental retardation and audio-visual impairment of the baby. Among them, human cytomegalovirus is the "culprit". It may not have any clinical manifestations after it invades the human body. At present, there are no safe and effective prevention and control measures at home and abroad. Therefore, the inspection of the above-mentioned pathogens has beco...

AI Technical Summary

Problems solved by technology

[0005] Chinese patent ZL.200420096377.3 and application number 200410080305.4 disclose a rapid diagnostic test tube for vacuum blood collection. Although the device can be used for joint inspection of several samples, it can also better solve the problems of iatrogenic infection and environmental pollution, but it has disadvantages Yes: (1) The structure of the device is complicated, the manufacturing cost is high, and the popularization is difficult

(2) The scope of application is limited

The device is only suitable for health technicians to collect blood from the subject for on-site testing, and for some samples that have been collected and prepared in advance, such as blood that has been collected and prepared, serum or plasma that has been separated and prepared, etc. Detection is powerless

(3) The use of vacuum test tubes for blood collection is far from being popularized in the majority of grassroots institutions and rural areas in my country, and vacuum blood collection also sometimes leads to accidents such as iatrogenic infection, pathogen dissemination, and environmental pollution due to failure of blood collection

In addition, Chinese patent application No. 200410099301.0 discloses a colloidal gold test strip that can jointly detect multiple pathogens, and Chinese patent application Nos. 02112230. Although these colloidal gold test strips and colloidal gold percolation devices can achieve various indicators in the joint inspection samples, there are still deficiencies: (1) the joint inspection indicators are all placed on a test paper, and each detection The cross-interference existing between

(2) Serum needs to be separated from the sample to be tested, which is not suitable for the detection of whole blood samples

Moreover, separating serum is not only time-consuming, but also requires certain equipment, reagents and conditions

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