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Traditional Chinese medicine for improving memory of learning and preventing memory failing

A technology for learning and memory impairment and learning and memory ability. It is applied in the fields of medical formula, drug combination, and drug delivery. It can solve problems such as difficult quality assurance, and achieve the effects of certain effects, good repeatability, and less prescription drugs.

Inactive Publication Date: 2012-10-03
JINAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But it also has the disadvantages that there are many drugs and the quality is difficult to guarantee

Method used

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  • Traditional Chinese medicine for improving memory of learning and preventing memory failing
  • Traditional Chinese medicine for improving memory of learning and preventing memory failing
  • Traditional Chinese medicine for improving memory of learning and preventing memory failing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Orthogonal design is used to study the animal model of memory impairment, observe the behavior and related biochemical indicators, and screen out the best and effective prescription of traditional Chinese medicine (that is, Q0409 screening recipe for the following experiments)

[0020] Kunming mice were housed in separate cages for males and females, free to eat and drink every day, and changed the litter regularly to keep the living environment of the mice clean and hygienic. At the same time, the mice in each group were administrated with the corresponding traditional Chinese medicine solution regularly every day.

[0021] Traditional Chinese medicine decoction-free granules, the above-mentioned traditional Chinese medicines are numbered A-G, Cistanche deserticola (A, 0.238g·mL -1 ), Morinda officinalis (B, 0.238g·mL -1 ), Polygala (C, 0.286g·mL -1 ), Fushen (D, 0.238g·mL -1 ), ginseng (E, 0.238g·mL -1 ), dried Rehmannia glutinosa (F, 0.238g·mL -1 ), Shichangpu (...

Embodiment 2

[0067] Using the animal model of learning and memory impairment to verify the effect of the traditional Chinese medicine Q0409 screening formula (CE±G) (Huperzine A as the control drug)

[0068] Kunming mice were housed in separate cages for males and females, free to eat and drink every day, and changed the litter regularly to keep the living environment of the mice clean and hygienic. At the same time, the mice in each group were administrated with the corresponding traditional Chinese medicine solution regularly every day.

[0069] Chinese medicine decoction-free granules, according to the results of Example 1, select CEG as the key research, CE as the main drug (positive effect, the greater the dose, the better), and G is the adjustment drug (negative effect, the smaller the dose, the better). C: Polygala; E: Ginseng; G: Shichangpu.

[0070] Traditional Chinese medicine solutions with different compatibility were prepared with double distilled water: Polygala (C, 0.286g·m...

Embodiment 3

[0099] Optimum Dosage Research of Drugs Using Animal Models of Learning and Memory Impairment

[0100] Kunming mice were housed in separate cages for males and females, free to eat and drink every day, and changed the litter regularly to keep the living environment of the mice clean and hygienic. At the same time, the mice in each group were administrated with the corresponding traditional Chinese medicine solution regularly every day.

[0101] According to the results of Example 2, CE was selected as the key research for Chinese medicine free decoction granules. C: Polygala; E: Ginseng; G: Shichangpu.

[0102] Traditional Chinese medicine solutions with different compatibility were prepared with double distilled water: Polygala (C, 0.286g·mL -1 ), ginseng (E, 0.238g·mL -1 ), Shichangpu (G, 0.286g·mL -1 ); huperzine A solution, the final concentration is about 3.8 μg·mL -1 . Randomize animals into groups:

[0103] Group 1: blank control group

[0104] Group 2: model gr...

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Abstract

The present invention discloses a Chinese medicine in the form of oral liquid, capsule, tablet, or mixture for improving memory power and preventing and treating dysmnesia, which is prepared from ginseng and polygala root through a conventional process in a way of oral liquid, capsule, troche, extractive and the like. The Chinese medicine provided by the invention is capable of resisting the aquired dysmnesia caused after an anticholinergic drug- scopolamine intraperitoneal injection, and has a Chinese medicine with the function for the growth of brain. Compared to other educational Chinese medicines, the Chinese medicine provided by the invention has good repeatability in test results, positive effect, less formula drugs with only two traditional Chinese medicines, and is easy to be obtained, convenient, and cheap.

Description

technical field [0001] The invention relates to the field of research, development and utilization of traditional Chinese medicine, in particular to a new prescription of intellectual-improving traditional Chinese medicine, which can obviously improve learning and memory impairment caused by medicine. Background technique [0002] Learning and memory ability is one of the basic abilities for human beings to understand the objective world, and it is also an important function of the human brain. With the gradual improvement of people's living standards, more and more people begin to pay attention to their own health problems. At present, due to social competition, the young people are under increased pressure in life and work, and there is a phenomenon of learning and memory loss; moreover, as our country enters an aging society, more and more elderly people are distressed by the loss of learning and memory In addition to suffering from various senile diseases, a considerabl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/69A61K9/08A61K9/10A61K9/20A61K9/48A61P25/00
Inventor 陆大祥戚仁斌王华东
Owner JINAN UNIVERSITY
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