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Novel formulation of shenqiwendan decoction and production method thereof

A production method, the technology of Wendan Decoction, which is applied in the direction of pill delivery, pharmaceutical formula, plant raw materials, etc., can solve the problems of commercial production, inconvenient carrying, and inability to store for a long time, so as to improve bioavailability and reduce adverse reactions , easy to carry effect

Active Publication Date: 2007-08-08
黄达驹 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Shenqi Wendan Decoction is a new dosage form of oral traditional Chinese medicine preparation, which has accurate dosage and stable quality, and is suitable for large-scale commercial production. Disadvantages of chemical production

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Embodiment 1 (Shenqi Wendan Decoction Oral Liquid):

[0067] Take 12 kg of pinellia, 12 kg of ginger, 40 kg of codonopsis, 40 kg of astragalus, 12 kg of bamboo, 12 kg of orange peel, 18 kg of tangerine peel, 6 kg of licorice, 10 kg of poria cocos and 6 kg of jujube. Add water to soak the medicinal materials for 0.5 hours; add water to decoct twice; the first time 2.5 hours, the second time 1 hour; combine the decoctions, filter, concentrate the filtrate under reduced pressure, add 95% ethanol to make the alcohol content reach 65%, static Set aside for 48 hours, recover ethanol, add distilled water to a total of 20L, stir well, filter, adjust pH to 6.5, potting, and sterilize to obtain.

Embodiment 2

[0068] Embodiment 2 (Shenqi Wendan Decoction Oral Liquid):

[0069] Decoct the medicinal materials twice, decoct for 1 hour for the first time, and 45 minutes for the second time, combine the medicinal liquid, filter, concentrate the filtrate to a relative density of 1.17 (80°C), cool, add 95% ethanol to make the alcohol content 65% Stand still for 48 hours to precipitate and filter, recover ethanol from the filtrate and concentrate to a relative density of 1.20 (80°C), add water to adjust to 1000L, add 3kg of cyclamate and 3kg of sodium benzoate, stir well, cool, filter, pot, and sterilize.

Embodiment 3

[0070] Embodiment 3 (Shenqi Wendan Decoction Oral Liquid):

[0071] Soak the medicinal materials in water for 1 hour, decoct twice according to the decoction method, the first time for 2 hours, and the second time for 1.5 hours. Combine the two decoctions, filter, and let the filtrate stand for 24 hours; take the supernatant, concentrate to 500L, add ethanol to make the alcohol content reach 60%; let stand for precipitation, filter, and recover ethanol; adjust the total amount of the filtrate to 1000L , add 2kg of sodium benzoate and 1kg of sodium cyclamate, mix well, seal in jars, and sterilize to get the product.

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PUM

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Abstract

The invention relates to a Chinese medicinal preparation and process for preparation, wherein the main raw materials include pinellia tuber, fresh ginger, pilose asiabell root, astragalus root, bamboo shavings, immature bitter orange, dried orange peel, licorice root, poria cocos wolf and jujube, and can be used for treating coronary disease and auricular fibrillation.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations and production methods thereof. [0002] The new dosage form of Shenqi Wendan Decoction is based on the dosage form of the traditional prescription Shenqi Wendan Decoction, and is developed by applying modern Chinese medicine theory and new technology, new technology and new equipment for the production of traditional Chinese medicine preparations. A new dosage form of traditional Chinese medicine oral preparations that embodies the characteristics of traditional Chinese medicine and can effectively control product quality. Specifically, it uses ten traditional Chinese medicinal materials such as Pinellia, ginger, Codonopsis pilosula, Astragalus membranaceus, Zhuru, Zhishi, tangerine peel, licorice, Poria cocos and jujube as the main raw materials. Phlegm-removing effect, mainly used for coronary heart disease, atrial fibrillation and other diseases, Shenqi Wendan ...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P9/10A61P9/00
Inventor 史冠君黄达驹张展飞何鹤锋
Owner 黄达驹
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