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Application of 'Gu Kang' medicine in preparation of formulations for treating osteoarthritis and osteoporosis

A technology for osteoarthritis and medicine, applied in the application field of Gukang medicine in the preparation of preparations for treating osteoarthritis and osteoporosis

Inactive Publication Date: 2009-10-07
贵州维康子帆药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The use of Gukang drugs for the treatment of osteoarthritis and osteoporosis, which belongs to liver and kidney insufficiency, has not been reported yet

Method used

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  • Application of 'Gu Kang' medicine in preparation of formulations for treating osteoarthritis and osteoporosis
  • Application of 'Gu Kang' medicine in preparation of formulations for treating osteoarthritis and osteoporosis
  • Application of 'Gu Kang' medicine in preparation of formulations for treating osteoarthritis and osteoporosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0121] Embodiment 1: Capsules

[0122]Take 600g of plantain root, 400g of sorrel, 600g of psoralen, 300g of Dipsacus, 150g of notoginseng, the above five flavors, take 30g of plantain root and notoginseng and grind them into fine powder, add water to the remaining plantain root and other three flavors of psoralen Decoct three times, each time for 1 hour, combine the decoction, concentrate the filtrate to a thick paste with a relative density of 1.31-1.35 (60°C), add the above-mentioned fine powder, mix well, dry, crush into fine powder, mix well, and put in 1 No. capsules, made into 1000 capsules, each containing 0.4g, 3-4 capsules each time, three times a day. One month is a course of treatment.

Embodiment 2

[0123] Embodiment 2: tablet

[0124] Take 500g of plantain root, 500g of sorrel, 550g of psoralen, 350g of Dipsacus, 100g of notoginseng, 50g of antler, and the above five flavors. For 1 hour, combine the decoction, concentrate the filtrate to a thick paste with a relative density of 1.20-1.35 (60°C), add the above fine powder, add appropriate amount of auxiliary materials such as starch, dextrin, and ethanol, and make 1000 tablets, 3-4 each time tablet, three times a day. One month is a course of treatment.

Embodiment 3

[0125] Embodiment 3: Granules

[0126] Take 200g of plantain root, 150g of sorrel, 350g of psoralen, 100g of Dipsacus, 150g of Epimedium, 50g of Panax notoginseng, and the above five flavors, add water to decoct three times, each time for 1 hour, combine the decoction, and concentrate the filtrate to relative density 1.20-1.35 (60 ℃) thick paste, dry, add sucrose:dextrin=4:1 as excipient to make 400g of granules, 6g each time, three times a day. One month is a course of treatment.

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Abstract

The invention discloses a new application of Gukang medicine. The present invention uses plantain root, sorrel, psoraleae, and Dipsacus as raw materials, obtains various extracts according to conventional processes, and then adds auxiliary materials to make oral and injection dosage forms suitable for clinical use, and is used for treating osteoarthritis. Arthritis and osteoporosis belong to liver and kidney deficiency. The invention not only provides a new clinical application for Gukang medicine, but also provides a new medicine for Chinese medicine treatment of osteoarthritis and osteoporosis belonging to liver and kidney deficiency.

Description

technical field [0001] The invention relates to a new clinical application of Gukang medicine, in particular to the application of Gukang medicine in preparing preparations for treating osteoarthritis and osteoporosis belonging to liver and kidney deficiency. It belongs to the technical field of medicines. technical background [0002] Osteoarthritis (OA) is a chronic joint disease characterized by focal articular cartilage degeneration, bone loss, joint edge osteophyte formation, joint deformity and subchondral bone density. , Degenerative osteoarthritis, and hypertrophic arthritis are the most common chronic and progressive rheumatic diseases after middle age. According to the X-ray census, the incidence rate is as high as 80% in the age group greater than 55 years old, and 1 / 8 of them have symptoms and activity disorders. At present, Western medicine still treats OA with anti-inflammatory analgesics and non-steroidal drugs and other symptomatic treatments, but the side ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61K36/487A61K36/185A61K9/00A61P19/08
Inventor 贺适鸣况明伦
Owner 贵州维康子帆药业股份有限公司
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