Heat-clearing and phlegm-resolving medicine composition, preparation and use thereof

A heat-clearing and phlegm-resolving and composition technology is applied in the field of pharmaceutical compositions for clearing heat and removing phlegm, which can solve the problems of loss of effective components, large clinical dosage, long processing time, etc. High utilization effect

Inactive Publication Date: 2009-04-01
成都利尔药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above preparation methods are all extracted at high temperature, which is not conducive to the preservation of active ingredients, and the processing time is long, which easily leads to the loss and destruction of active ingredients
And the current commercially available bamboo leek product is prepared by the traditional bamboo leek method, and it is an oral liquid. It is 1.0ml / kg / day, the clinical dosage is large, and the oral liquid is inconvenient to carry, the dosage is difficult to control, the liquid preparation is not easy to store, and it is easy to cause secondary pollution during use

Method used

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  • Heat-clearing and phlegm-resolving medicine composition, preparation and use thereof
  • Heat-clearing and phlegm-resolving medicine composition, preparation and use thereof
  • Heat-clearing and phlegm-resolving medicine composition, preparation and use thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Embodiment 1 Preparation of medicinal raw material extract extractum of the present invention

[0031] a. Cut 100g of fresh bamboo stalks of pink green bamboo into 2-5cm, put them in a 1000ml beaker, add 6 times the amount of water, control the temperature at 100°C, boil for 1.5 hours, filter the decoction, and add 4 Double the amount of water at 100°C, decoct for 1.0 hour, filter, combine the two filtrates, add distilled water to 1000ml to constant volume (each 1ml is equivalent to 0.1g of fresh Danzhu).

[0032] b. Concentrating the bamboo extract in step a (temperature below 80° C., specific gravity > 1.01) in three effects to obtain a bamboo leach concentrate. Process parameters: vapor pressure: ≤0.10Mpa; temperature: first effect: 75--85°C; second effect: 65--75°C; third effect: 55--65°C; vacuum degree: first effect: 0.020-0.040Mpa; Two-effect: 0.040-0.060Mpa; Three-effect: 0.060-0.080Mpa; Specific gravity of cream collection: 1.10-1.35 (40--80℃).

[0033] c. Dry...

Embodiment 2

[0038] Embodiment 2 Preparation of medicine bamboo extract extractum of the present invention

[0039]a. Cut 100g of fresh bamboo stalks of Elephant bamboo into 2-5cm, put it in a 1000ml beaker, add 6 times the amount of water, control the temperature at 100°C, boil for 1.5 hours, filter the decoction, and add 4 times the amount of filter residues respectively Water, temperature 100°C, decoct for 1.0 hour, filter, combine the two filtrates, add distilled water to 1000ml to constant volume (each 1ml is equivalent to 0.1g of fresh bamboo).

[0040] b. Add the bamboo extract into the decompression concentration tank, control the temperature at 60° C., and control the vacuum pressure at 0.08 Pa, and concentrate for 6 hours to obtain the bamboo extract concentrate;

[0041] c. Drying method: boiling drying.

[0042] The above comparative experiments show that the medicinal raw material extract of the present invention is not equal to the traditional roasted fresh bamboo leek, and ...

Embodiment 3

[0043] Embodiment 3 Preparation of pharmaceutical tablet of the present invention

[0044] Take an appropriate amount of starch and dextrin, mix them evenly, spray into the clear paste prepared in step b of Example 1, and granulate in one step, the spray frequency is 4HZ, the pressure is 0.12MPa, the material temperature is 40-50°C, the air inlet temperature is 75-85°C, and the air outlet The temperature is 70-75°C. The granules are mixed with 0.5% magnesium stearate, pressed into 1000 tablets, film-coated, subpackaged, and obtained.

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Abstract

A Chinese medicine for antipyresis and resolving phlegm is prepared from fresh P. glauca Mcclure or phyllostachys glance McClure or phyllostanchys nuda McClure and pharmacologically acceptable auxiliary through extracting. Its advantages are high biologic utilization rate, and high quality stability.

Description

technical field [0001] The invention relates to a medicinal composition for clearing away heat and resolving phlegm, in particular to a medicinal composition prepared from plant extracts, belonging to the field of medicine. Background technique [0002] Fresh bamboo lek, also known as bamboo juice, light bamboo lek, bamboo oil, etc. This product is the juice that flows out from the fresh stalks of the Gramineae Phyllostachys edulis or Bamboo spp., which is commonly used for clearing away heat and resolving phlegm. Sweet in taste and cold in nature, home to the heart, lungs, stomach meridian, extremely smooth in nature. Function: clearing heat and relieving fire, moistening lung and smoothing phlegm, nourishing yin and nourishing, benefiting orifices and improving eyesight. It is often used for symptoms of lung heat and phlegm congestion, phlegm fanning and heat, phlegm heat convulsions, apoplexy, depression and thirst, blood deficiency and spontaneous sweating. According t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61K9/16A61K9/20A61K9/22A61K9/48A61K9/52A61P11/10A61K135/00
Inventor 刘波魏岚向光才代德芬鲍文娟叶犁
Owner 成都利尔药业有限公司
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