Chinese traditional medicine orthopaedics preparation for improving effect of medicine and preparation method thereof

An orthopaedic and preparation technology, applied in the field of traditional Chinese medicine orthopedic preparations and preparation, can solve the problems of inability to quantitatively and effectively control product quality, lack of content control methods in Guxian tablets, etc.

Inactive Publication Date: 2008-12-17
叶耀良
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no relevant public technology related to the production methods and pharmacological effects of Guxian Dropping Pills, Dispersible Tablets, and Soft Capsules. The prior art of Guxian Tablets lacks a method for content control, and cannot quantitatively and effectively control product quality.

Method used

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  • Chinese traditional medicine orthopaedics preparation for improving effect of medicine and preparation method thereof
  • Chinese traditional medicine orthopaedics preparation for improving effect of medicine and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0112] Embodiment 1: the preparation of medicinal material extract:

[0113] Drynaria 92g Rehmannia glutinosa 207g Black beans 125g

[0114] Ligustrum lucidum 92g Achyranthes bidentata 59g Curculigo 59g

[0115] Cuscuta 125g Fangji 92g Lycium barbarum 59g

[0116] Take the above medicinal materials according to the weight ratio of the above components, add 60% ethanol to the dodder and cold soak three times, the first time is 48 hours, the second and third times are 24 hours each, combine the soaking liquid, filter, and recover the ethanol from the filtrate to an appropriate amount; take bone fragments Tonic, Rehmannia glutinosa, black beans, Ligustrum lucidum, Achyranthes bidentata, Curculigo, Fangji, Lycium barbarum eight herbs, add 6 times the amount of water, decoct twice, each time for 2 hours, combine the decoction, filter, and the filtrate is the same as the above The extracts are combined and concentrated to a thick paste with a relative density of 1.25 (40°C), which...

Embodiment 2

[0117] Embodiment 2: the preparation of medicinal material extract:

[0118] Drynaria 102g Rehmannia glutinosa 217g Black beans 135g

[0119] Ligustrum lucidum 102g Achyranthes bidentata 69g Curculigo 69g

[0120] Cuscuta 135g Fangji 102g Goji berries 69g

[0121] According to the weight ratio of the above components, take nine kinds of medicinal materials, add 70% ethanol to the dodder and cold soak three times, the first time is 48 hours, the second and third times are 24 hours each, combine the soaking liquid, filter, and recover the ethanol from the filtrate to an appropriate amount; take the bone Drynariae, Rehmannia glutinosa, black beans, Ligustrum lucidum, Achyranthes bidentata, curculigo, Fangji, medlar eight herbs, add 9 times the amount of water, decoct twice, 2 hours each time, combine decoction, filter, filtrate and The above extracts are combined and concentrated to a thick paste with a relative density of 1.38 (50°C), which is the medicinal material extract, o...

Embodiment 3

[0122] Embodiment 3: the preparation of medicinal material extract:

[0123] Drynaria 112g Rehmannia glutinosa 227g Black beans 145g

[0124] Ligustrum lucidum 112g Achyranthes bidentata 79g Curculigo 79g

[0125] Cuscuta 235g Fangji 112g Lycium barbarum 79g

[0126] According to the weight ratio of the above components, take the nine medicinal materials, add 80% ethanol to the dodder and cold-soak three times, the first time is 48 hours, the second and third times are 24 hours each, combine the soaking liquid, filter, and recover the ethanol from the filtrate to an appropriate amount; take the bone Drynariae, Rehmannia glutinosa, black beans, Ligustrum lucidum, Achyranthes bidentata, curculigo, Fangji, and medlar, add 15 times the amount of water, decoct twice, each time for 2 hours, combine the decoction, filter, and filtrate with The above extracts are combined and concentrated to a thick paste with a relative density of 1.40 (60°C), which is the medicinal material extrac...

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Abstract

The invention discloses a Chinese traditional medicine orthopaedics preparation for improving effect of medicine and preparation method, wherein the medicine comprises drynaria, prepared rehmannia root, black soya bean, ligustrum japonicum, achyranthes and cyathula root, curculigo rhizome, dodder seed, tetrandra root, wolferry fruit. The adjuvant or base material include drop pill base material 150-750 to prepare drop pill, or dispersion medium 50-380, suspension adjuvant 10-40 and emulsifying agent_10-150, emulsifying adjuvant 10-150 to prepare soft capsule, or filling agent 60-320, crumbling agent 6-100, lubricating agent 0.5-3 to prepare dispersion tablet.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine orthopedic preparation and a preparation method for improving drug efficacy. technical background [0002] Guxian Tablets are composed of Rehmannia glutinosa, Ligustrum lucidum, Lycium barbarum, black beans, Drynaria rhizome, Cuscuta, Curculigo, Fangji, Achyranthes bidentata, etc. Its main function is to nourish the kidney and strengthen the foundation. Pharmacological and clinical tests have shown that it has obvious anti-inflammatory and analgesic effects and increases the immune function of the body. The preparation is mainly effective in treating cervical spondylosis, lumbar hypertrophic spondylitis, various bone and joint spurs and heel spurs, followed by knee joint spurs, lumbar hypertrophic spondylitis and cervical spondylosis. For periarthritis of the shoulder and sciatica, it can also relieve symptoms and improve function. Commercially available Guxian Tablets are sugar-coated t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/88A61K36/815A61K36/804A61K36/59A61K36/39A61K36/21A61K36/185A61K36/11A61P19/08
Inventor 叶耀良廖志钟
Owner 叶耀良
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