Medicine composition for treating cardiac and cerebral vascular diseases
A technology for cardiovascular and cerebrovascular diseases and compositions, which is applied in the field of pharmaceutical compositions whose active ingredients are medicinal active ingredients, and can solve problems such as difficulty in obtaining satisfactory curative effect of drugs, complex causes of disease, and numerous influencing factors
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Embodiment 1
[0018] A single pure ligustilide was obtained by separation and purification of the volatile oil of Rhizoma Chuanxiong respectively, and the volatile oil of Acorus was obtained from the medicinal material of Acorus acorus by steam distillation. Take 2 g of ligustilide, 10 g of volatile oil of Acorus calamus (which contains 39.6% of β-asarone), add 120 g of soybean oil for injection, preheat to 55°C as the oil phase, and set aside. Take another 12g of soybean lecithin for injection, add 500ml of water for injection to disperse, then add 25g of glycerin for injection, stir to dissolve, heat to 55°C, and continue to stir, while slowly adding the oil phase, and homogenize at high speed for 6 minutes to prepare colostrum. Pass the colostrum through a high-pressure homogenizer for 4 cycles to obtain a submicron emulsion. Under low-speed stirring, add submicron emulsion and water for injection to 1000ml, filter, subpackage, and sterilize to obtain emulsion injection.
Embodiment 2
[0020] The volatile oil of Ligusticum chuanxiong was obtained from the medicinal material of Rhizoma Chuanxiong by steam distillation; the medicinal material of Shichangpu was obtained by supercritical CO 2 Extract the volatile oil of Shichangpu. Take 6g of Chuanxiong volatile oil (containing 35.1% of ligustilide) and 20g of Shichangpu volatile oil (including 53.1% of β-asarone), add them to the PEG-6000 melt, stir and mix, and make it in a dropping pill machine 5000 drop pills are the described pill form medicine.
Embodiment 3
[0022] Take 15g of ligustilide and 15g of volatile oil of Shichangpu, add 40g of soybean oil, and use it as the oil phase for later use. Take 3g of egg yolk lecithin, 12g of glycerin, 5g of tragacanth gum, 0.5g of ethylparaben and an appropriate amount of food flavor, add 250ml of distilled water, stir to dissolve, heat to 70°C, and continue to stir, while slowly adding the oil phase, high-speed Homogenize for 8 minutes to prepare colostrum, circulate the colostrum through a high-pressure milk homogenizer for 6 times, add distilled water to 500ml under low-speed stirring, filter, pack, put it in a special nasal drop bottle or a spray bottle, and get the nasal drop Sprays and sprays.
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