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Wound-Healing Pharmaceutical Compositions in the Form of a Cream Based on Amino Acids and Sodium Hyaluronate

a technology of amino acids and pharmaceutical compositions, applied in the field of wound healing pharmaceutical compositions in the form of creams based on amino acids and sodium hyaluronate, can solve the problems of paralysis or bedridden, liable to ischaemic necrosis and ulceration of the tissues covering the projection of bones,

Inactive Publication Date: 2008-11-20
PROFESSIONAL DIETETICS SPA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention relates to a wound-healing pharmaceutical composition in the form of a cream that contains a combination of amino acids and sodium hyaluronate. The composition has been found to promote faster wound healing and reduce the need for surgery or debridement. It has also been found to be effective in treating skin aging and promoting skin regeneration. The composition is applied to the affected area after removing any foreign material and excess blood with sterile gauze. The active ingredients in the composition include glycine, L-proline, sodium hyaluronate, and possibly L-lysine hydrochloride and L-leucine. The composition is safe and effective for the treatment of various types of wounds, including surgical wounds, vaginal and rectal lesions, buccal wounds, and serious burns.

Problems solved by technology

In the absence of suitable preventive actions, patients who are paralysed or bedridden for long periods are liable to ischaemic necrosis and ulceration of the tissues covering projecting bones, especially in the sacral, ischial, malleolar, heel and great trochanter regions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example

[0044]

%INGREDIENTSCompositionPurified water82.27Sodium hyaluronate1.33Glycine1.00L-Proline0.75L-Leucine0.15L-Lysine HCl0.10Cetyl stearyl octanoate (Saboderm CSO)6.00Acrylic acid and vinyl ester copolymer (Stabylen30)0.30Cetyl stearyl alcohol (Lanette O)4.00Potassium cetyl phosphate (Amphisol K)3.00Imidazolidinyl urea (Preservative G)0.30Phenoxyethanol-parabens (Sepicide Hb2)0.6032% Sodium hydroxide0.20

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Abstract

This invention relates to wound-healing pharmaceutical or cosmetic (anti-skin aging) compositions in the form of a cream based on amino acids and sodium hyaluronate.

Description

FIELD OF INVENTION[0001]The present invention relates to wound-healing pharmaceutical compositions in the form of a cream based on amino acids and sodium hyaluronate.PRIOR ART[0002]In the absence of suitable preventive actions, patients who are paralysed or bedridden for long periods are liable to ischaemic necrosis and ulceration of the tissues covering projecting bones, especially in the sacral, ischial, malleolar, heel and great trochanter regions.[0003]Bedsores and chronic ulcerous wounds are usually treated with gentle massage to restore the circulation, possibly with mechanical removal of the necrotic tissue and cleansing with soap (which can cause oedema or dehydration), or with hydrophilic polymers, hydrogen peroxide or alcohol rubs (which can cause damage because the removal of the fats in the cutaneous tissue dries and cracks the skin).[0004]Serious burns also require debridement of the affected area and removal of necrotic tissue.DESCRIPTION OF THE INVENTION[0005]It has n...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K31/728A61P17/02
CPCA61K31/198A61K31/728A61K31/401A61P17/00A61P17/02A61P39/06A61P43/00
Inventor CONTI, FRANCO
Owner PROFESSIONAL DIETETICS SPA
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