Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Deer antler extract for promoting angiogenesis

a technology of angiogenesis and antler, which is applied in the field of angiogenesis extracts, can solve the problems of increasing the number of micro vessels in the treated wound, slow healing process, and paper that did not contain data showing actual angiogenic or wound healing activity, and achieves the effect of promoting angiogenesis and proliferating endothelial cells

Inactive Publication Date: 2007-02-01
VELVET ANTLER RES NEW ZEALAND
View PDF3 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

"The present invention provides an isolated extract of deer velvet that contains components with molecular weights of less than 10 kDa that have a proliferative effect on endothelial cells and promote angiogenesis. The components can be heated, sterilized, or freeze thawed without losing their effectiveness. The isolated extract or peptides from the extract can be used to make a medicament for the treatment of wounds. The medicament can be in the form of a gel, lotion, balm, spray, or transdermal dressing. The invention also provides a method of treating wounds by administering the medicament to an animal in need. The invention also provides a composition that includes the isolated extract or peptides for the treatment of wounds. The components of the invention can be determined by various methods such as gel filtration chromatography, electrophoresis, or mass spectrometry."

Problems solved by technology

Generally, most commonly used therapies for treating persistent wounds do not assist the wound to provide its own blood supply and therefore the healing process is slow.
This resulted in increased numbers of micro vessels in the treated wounds.
Importantly however, this paper did not contain any data showing actual angiogenic or wound healing activity.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Deer antler extract for promoting angiogenesis
  • Deer antler extract for promoting angiogenesis
  • Deer antler extract for promoting angiogenesis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0080] Experimental

[0081] Methods

[0082] Collection of Tissue:

[0083] Deer velvet antlers were collected from 3-year-old red deer stags at 55-60 days of growth following casting of the previous antlers.

[0084] The velvet was removed according to the regulations laid down by Code of Recommendations and Minimum Standards for the Welfare of Deer during the Removal of Antlers, July 1992 (revised 1997), Ministry of Agriculture and Fisheries, Wellington, New Zealand.

[0085] The velvet was commercially processed by hot dipping or freeze-drying. Hot dipping is based on the traditional Chinese method, where sticks of antler are suspended from the base (i.e. tips downwards) and repeatedly dipped into almost boiling water for brief periods of time. After being dipped, they are allowed to cool before being dipped again. Dipping continues until clear plasma bubbles from the cut bases of the antlers. Antlers are then placed in a low humidity drier at approximately 15° C. for several weeks until ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
molecular weightsaaaaaaaaaa
temperatureaaaaaaaaaa
temperatureaaaaaaaaaa
Login to View More

Abstract

An isolated extract of deer velvet which contains components which have molecular weights that are substantially less than or equal to 10 kDa and which have a proliferative effect on endothelial cells and / or promote angiogenesis.

Description

TECHNICAL FIELD [0001] This invention relates to a deer antler extract In particular, the present invention relates to angiogenic extracts obtained from-deer antler velvet, and compositions containing said extracts for use in the treatment of wounds, injuries and diseases in human and animal medical practice. BACKGROUND ART [0002] Wounds, in particular persistent wounds, which are difficult to heal, require a blood supply that can nourish the wound and mediate the healing process and minimize scar formation. Generally, most commonly used therapies for treating persistent wounds do not assist the wound to provide its own blood supply and therefore the healing process is slow. [0003] Various therapies for the treatment of chronic wounds exist, however, the use of compression bandages still appears to be a common treatment (Marshall et al., 2001). Other therapies are available and some natural therapies have been proposed that work through mechanisms involving regulation of oxygen tens...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61K35/12A61K35/36
CPCA61K35/36A61P17/02A61P9/00C07K14/47C07K1/14
Inventor COATES, DAWN ELIZABETHHAINES, STEPHEN ROYSUTTIE, JAMES MILLER
Owner VELVET ANTLER RES NEW ZEALAND
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com