Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for treatment of reactive arthritis or bursitis

a bursitis and reactive arthritis technology, applied in the field of reactive arthritis or bursitis treatment, can solve the problems of chronic pain syndrome and loss of use of joints

Inactive Publication Date: 2005-08-11
BONNER ERNEST L JR +1
View PDF24 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

"The patent describes a combination of three drugs, acyclovir, minocycline hydrochloride, and metronidazole, for the treatment of reactive arthritis and bursitis. This combination has shown promising results in reducing symptoms and even curing the diseases. The drugs can be administered in various forms such as capsules, tablets, or injections. The technical effect of this patent is to provide a method for effectively treating reactive arthritis and bursitis by using a combination of drugs that targets the underlying causes of the diseases."

Problems solved by technology

In the long term, bursitis can result in loss of use of a joint and chronic pain syndrome.
Unfortunately, current procedures for management treat the symptoms of these diseases rather than their underlying pathogens.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0031] A 77 year old female presented with complaints of neck, upper back, lower back, bilateral shoulder, bilateral wrist, digits of hands, bilateral hip, and bilateral ankle pains of years duration. The patient complained of associated stiffness in those same joints. Her physical examination was remarkable for tenderness at her neck, right shoulder, elbow bilaterally, wrist bilaterally, the metacarpal phalangeal and the proximal interphalangeal joints of her right hand, hip bilaterally, knee bilaterally, and the Achilles insertion area bilaterally. The Sed rate and rheumatoid factors were normal. This patient was diagnosed with reactive arthritis and was started on a treatment consisting of 125 mg of metronidazole, 250 mg of valacyclovir hydrochloride, and 50 mg of minocycline hydrochloride twice daily. After 69 days of such treatment, the patient noted pain in the palm of her left hand only. She further denied any stiffness. Physical examination on the 69th day did not reveal any...

example 2

[0032] A 52 year old male presented with complaints of bilateral knee and left wrist pain. He also noted associated morning stiffness. He was treated with minocyline hydrochloride 100 mg BID and acyclovir 400 mg BID. This resulted in significan improvement, but not total resolution of his complaints of pain and stiffness in his knees and left wrist.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
stiffnessaaaaaaaaaa
swellingaaaaaaaaaa
movementaaaaaaaaaa
Login to View More

Abstract

A method for treatment for conditions in human beings associated with either or both reactive arthritis or bursitis comprising administering a combination of member of the family of synthetic purine nucleoside analog antiviral drugs, a member of the tetracycline family, and a member of the nitroimidazole family, or alternatively, administering a combination of a member of the family of synthetic purine nucleoside analog antiviral drugs, a member of the quinolone family, and a member of the nitroimidazole family.

Description

[0001] This is a continuation of application Ser. No. 10 / 896,612 filed Jul. 20, 2004, still pending, which was a continuation of application Ser. No. 10 / 271,117 filed Oct. 15, 2002, now U.S. Pat. No. 6,765,000, which was a continuation of application Ser. No. 09 / 510,704, filed Feb. 22, 2000, now U.S. Pat. No. 6,465,473, which was a continuation-in-part of application Ser. No. 09 / 270,962, filed Mar. 17, 1999, now U.S. Pat. No. 6,087,382.BACKGROUND OF THE INVENTION [0002] This invention relates to an improved method for treatment of symptoms associated in humans with reactive arthritis or idiopathic bursitis. [0003] Reactive arthritis refers to a spondyloarthritity which usually arises as a complication of an infection elsewhere in the body. Reactive arthritis can be caused by species of Shigella bacteria (most notably Shigella flexneri), Yersinia enterocolitica, Campylobacter jejuni, several species of Salmonella, genitourinary pathogens, Chlamydia trachomatis, Neisseria gonorrhea, U...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(United States)
IPC IPC(8): A61KA61K31/198A61K31/415A61K31/4164A61K31/4172A61K31/4406A61K31/519A61K31/52A61K31/522A61K31/65
CPCA61K31/198A61K31/4164A61K31/4406A61K31/522A61K31/65A61K2300/00A61P13/02A61P13/08A61P15/00A61P19/02A61P27/02
Inventor BONNER, ERNEST L.HINES, ROBERT
Owner BONNER ERNEST L JR
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com