Dual ligand sol-gel sorbent combining superhydrophobicity and Π-Π interaction

Abstract

A method of coating at least one silica capillary using a novel dual ligand sol-gel sorbent and method of manufacture of such sorbent is provided herein. The dual ligand sol-gel sorbent provides superior enrichment effects through simultaneous exploitation of superhydrophobicity of one of the ligands and the ability of the other ligand to undergo π-π interaction with hydrophobic aromatic analytes. Sorbent performance is enhanced both in terms of analyte enrichment and sorbent stability, such as pH stability and solvent stability.

Description

CROSS REFERENCE TO RELATED APPLICATIONS[0001]This application is a divisional of and claims priority to U.S. application Ser. No. 15 / 813,799, entitled “Dual Ligand Sol-Gel Sorbent Combining Superhydrophobicity and 71-71 Interaction”, filed Nov. 15, 2017, now U.S. Pat. No. 10,967,356 which is a nonprovisional of and claims priority to U.S. Provisional Patent Application No. 62 / 422,417, entitled “Dual Ligand Sol-Gel Sorbent Combining Superhydrophobicity and π-π Interaction”, filed Nov. 15, 2016, the entire contents of each of which are herein incorporated into this disclosure.FIELD OF INVENTION[0002]This invention relates to sorbents. Specifically, the invention relates to dual ligand sol-gel sorbents having enhanced qualities.BACKGROUND OF THE INVENTION[0003]Solid-phase microextraction (SPME) is a solvent-free, environmentally benign sample preparation technique. (R. P. Belardi, J. B. Pawliszyn, The application of chemically modified fused silica fibers in the extraction of organics ...

AI Technical Summary

Benefits of technology

This patent presents a new method for extracting nonpolar analytes using a sol-gel sorbent that has two surface-bonded organic ligands. The sol-gel coatings prepared using this method have superior enrichment of nonpolar analytes by exploiting the superhydrophobicity of one ligand and the π-π interaction ability of the other. The use of germania in the sol-gel substrate also enhances the stability of the sorbent. The prepared sol-gel coatings provide low limits of detection and excellent reproducibility in extracting various analytes from saline samples.

Problems solved by technology

However, transferring the extracted analytes to liquid-phase separation systems (e.g., HPLC, CE, etc.) may require complicated sample transfer interfaces.

Even though fiber SPME has gained significant popularity, its operation using conventionally created coatings still faces some inherent disadvantages mainly due to the lack of chemical bonds between the coated extraction medium and the fiber surface.

As a result, conventionally prepared SPME coatings are not able to provide exceptional thermal- and solvent stability, and this sometimes puts limitations on their analytical potential when used in hyphenation with GC or HPLC.

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