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Use of wasp's nest in preparing medicine for preparing endometriosis

A technology of endometrium and exposed hives, applied in the direction of drug combination, medical raw materials derived from arthropods, diseases, etc., can solve problems such as easy recurrence, high price, liver function damage, etc.

Inactive Publication Date: 2007-01-24
SHANGHAI CHANGHAI HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the decrease in the level of this diol, the patient has a change similar to that of menopause, which brings more obvious side effects
At the same time, these drugs are expensive, and long-term use can cause liver damage, and they are prone to relapse after drug withdrawal. These shortcomings limit the application of these drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Decoction:

[0013] Take 75.6g of dew honeycomb, wash it, put it into the decocting pot, add water until it is 5cm higher than the medicine, soak for half an hour, boil it, then decoct for half an hour, get the juice, and then decoct twice according to the above method, Take the juice. The 3 medicinal juices are mixed and bottled to make a finished product. This dose of medicinal liquid is a weekly dosage for 15 rats.

Embodiment 2

[0015] 1 Material:

[0016] 1.1 Experimental animals:

[0017] 60 healthy, sexually mature unmated female SD rats, aged 70d-80d, each rat weighing 160-180g. The rats were provided by the Animal Center of Fudan University School of Medicine, and were kept in the animal room of the Animal Experiment Center of this hospital with 12 hours of light and 12 hours of darkness.

[0018] 1.2 Main equipment:

[0019] Forma725 -80°C low-temperature refrigerator (USA), BCD-248 ordinary refrigerator (Qingdao Haier Group), Olympus PM-10AD microscope (Japan OLYMPUS company), high-speed low-temperature centrifuge (Germany Hereaus company), Access automatic particle chemistry Luminescence analyzer (Beckman Coulter, USA), Array 360 specific protein analyzer (Beckman Coulter, USA), homogenizer, wet box, incubator, wax dipping box, embedding box, slicer , oven, etc.

[0020] 1.3 Main reagents:

[0021] Cytochrome aromatase P450 monoclonal antibody (purchased from Beijing Zhongshan Bioengineer...

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Abstract

The present invention discloses the application of wasp's nest in preparing medicine for treating endometriosis. Animal test proves the obvious endometriosis treating effect of wasp's nest, and what is more important is that wasp's nest possesses inapproachable safety compared with danazol. With high treating effect and basically no adverse effect, wasp's nest possesses excellent application foreground in treating endometriosis.

Description

technical field [0001] The invention relates to a new application of dew hives, in particular to the application of dew hives in the preparation of medicines for treating endometriosis. Background technique [0002] Endometriosis is the appearance of functional endometrium outside the inner wall of the uterine cavity. It causes secondary dysmenorrhea, infertility, chronic pelvic pain and other symptoms that seriously affect the quality of life of patients. Although endometriosis is a benign gynecological disease, it is aggressive, extensively planted, and prone to recurrence, which is very similar to malignant tumors. Endometriosis is a common and frequently-occurring disease among women of childbearing age, with an incidence rate as high as 15%, and the incidence rate is increasing year by year. Although endometriosis has been discovered for more than 100 years, and the pathogenesis of endometriosis has been deeply and extensively studied over the years, its exact pathoge...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/64A61P15/00
Inventor 俞超芹石书芳
Owner SHANGHAI CHANGHAI HOSPITAL
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